<原著>SaikosaponinsとGinsengsaponinsの生体膜に及ぼす作用 : (1)SaikosaponinsとGinsengsaponinsの溶血活性

概要

論文の詳細を見る
Saikosaponins and ginsengsaponins were extracted and purified from Bupleurum falcatum L. and Panax ginseng C. A. Meyer respectively, and their structures were already determined. Many investigations on the pharmacological actions of ginsengsaponins and saikosaponins have been reported. The action of saikosaponins for hepatitis and the central depressant action of ginsengsaponins are well known. On the other hand, the hemolytic activity of saponins has been also studied for a long time. It is a very important and interesting problem to clarify the action between saponins and biological membranes and the mechanism of hemolysis by saponins. In this paper the morphological changes of red blood cells by saikosaponins and ginsengsaponins and the relationship between the surface tension of these saponins and the hemolytic activity were studied.
近畿大学の論文
1978-09-25