mRNA Expression of Lysyl Oxidase and Matrix Metalloproteinase-12 in Mouse Skin
スポンサーリンク
概要
- 論文の詳細を見る
Elastic fibers in the dermis play an important role in skin elasticity. The desmosine crosslinking structure constructed of lysyl oxidase (LOX) in elastic fibers contributes to elasticity, while elastic fibers are primarily degraded by one of the matrix metalloproteinases (MMPs), MMP-12. We investigated the gender differences and diurnal variation of these enzymes. Gender-based differences in LOX mRNA expression were detected, and were significantly lower in females. In contrast, higher MMP-12 mRNA expression was observed in the light period, suggesting that elastic fibers might be degraded in the light rather than the dark period.
- 社団法人 日本農芸化学会の論文
- 2008-11-23
著者
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Shimizu Makoto
Graduate School Of Agricultural And Life Sciences The Univ. Of Tokyo
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Furuse Mitsuhiro
Laboratory Of Advanced Animal And Marine Bioresources Faculty Of Agriculture Kyushu University
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Morimatsu Fumiki
R&d Center Nippon Meat Packers Inc.
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Takahata Yoshihisa
R&d Center Nippon Meat Packers Inc.
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Takahata Yoshihisa
Research And Development Center Nippon Meat Packers Inc.
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Sato Mikako
R&d Center Nippon Meat Packers Inc.
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ONITSUKA Eiichiro
Research and Development Center, Nippon Meat Packers, Inc.
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HAMASU Kousuke
Laboratory of Advanced Animal and Marine Bioresources, Graduate School of Bioresource and Bioenviron
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Takahata Yoshihisa
R&d Center Nippon Meat Packers Inc
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Morimatsu Fumiki
Research And Development Center Nippon Meat Packers Inc.
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Sato Mikako
Research And Development Center Nippon Meat Packers Inc.
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Oikawa Daichi
Laboratory Of Advanced Animal And Marine Bioresources Graduate School Of Bioresource And Bioenvironm
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MIZOBE Yurika
Laboratory of Advanced Animal and Marine Bioresources, Graduate School of Bioresource and Bioenviron
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TSUYAMA Shoichiro
Laboratory of Advanced Animal and Marine Bioresources, Graduate School of Bioresource and Bioenviron
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AKIMOTO Yoriko
Laboratory of Advanced Animal and Marine Bioresources, Graduate School of Bioresource and Bioenviron
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Onitsuka Eiichiro
Research And Development Center Nippon Meat Packers Inc.
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Akimoto Yoriko
Laboratory Of Advanced Animal And Marine Bioresources Graduate School Of Bioresource And Bioenvironm
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Furuse Mitsuhiro
Laboratory Of Advanced Animal And Marine Bioresources Graduate School Of Bioresource And Bioenvironm
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Mizobe Yurika
Laboratory Of Advanced Animal And Marine Bioresources Graduate School Of Bioresource And Bioenvironm
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Hamasu Kousuke
Laboratory Of Advanced Animal And Marine Bioresources Graduate School Of Bioresource And Bioenvironm
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Tsuyama Shoichiro
Laboratory Of Advanced Animal And Marine Bioresources Graduate School Of Bioresource And Bioenvironm
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