メニエール病に対するイソソルビド液状とゼリー状の治療効果と服薬コンプライアンスの比較検討

概要

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Most patients with Menieres disease can be successfully treated with medication. In Japan, since the 1980s we have usually used osmotic diuretics, such as Isosorbide-liquid to control the inner ear endolymphatic hydrops. We have, however, had problems in that Menieres patients sometimes complain of the tough regimen involving taking Isosorbide-liquid on a daily basis. Recently, Isosorbide-jelly has been developed to improve the medication compliance for patients with Menieres disease. In the present study, we examined differences between the effects of Isosorbide-liquid and Isosorbide-jelly on hearing and vertigo. We also compared the medication compliance of Isosorbide-liquid with that of Isosorbide-jelly. There were no significant differences in hearing level and vertigo frequency in Menieres patients before and after Isosorbide-liquid was changed to Isosorbide-jelly. Regarding medication compliance, we should consider which Isosorbide-type we use for each patient on an individual basis.
日本めまい平衡医学会の論文
2008-08-01