Effects of Intestinal Microflora on the Bioavailability of Dietary Quercetin in Adult Mice
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概要
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The effects of intestinal microflora on the bioavailability of dietary quercetin in adult mice were studied. The control group was given a casein diet and water ad libitum. The antibiotics-treated group was given a casein diet and water that contained penicillin and streptomycin ad libitum. Fecal beta-glucuronidase activity was significantly greater in the control mice than in the antibiotics-treated mice. The concentrations of quercetin and isorhamnetin, after deconjugation of plasma quercetin metabolites, were significantly greater in the antibiotics-treated mice. The cecal pools of quercetin in the antibiotics-treated mice were significantly greater than those in the control mice. In untreated mice, it may be necessary to reduce the scission of quercetin and quercetin metabolites and greater beta-glucuronidase activity of the microflora might be needed to maintain a higher concentration of plasma quercetin metabolites.
- 社団法人 日本食品科学工学会の論文
- 2000-11-01
著者
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Suzuki Hiramitsu
香川栄養学園 ハイテクリサーチセンター
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Suzuki Hiramitsu
High Technology Research Center Kagawa Nutrition University:laboratory Of Food Science And Technolog
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SUZUKI Hiramitsu
National Food Research Institute
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Tamura Motoi
Department Of Food Science And Technology Faculty Of Agriculture Kyushu University
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Shinohara Kazuki
National Food Res. Inst. Ibaraki Jpn
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Tamura Motoi
National Food Res. Inst. Ibaraki Jpn
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Suzuki Hisashi
Food Processing Technology Center Gifu Prefectural Research Institute Of Industrial Product Technolo
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Tamura Motoi
National Food Research Institute Ministry Of Agriculture Forestry And Fisheries
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