1991年度ノ-ベル医学・生理学賞--イオンチャンネル研究の画期的手法を開発
スポンサーリンク
概要
著者
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中山 仁
Faculty Of Pharmaceutical Sciences Kumamoto University
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金岡 裕一
Faculty Of Pharmaceutical Sciences Hokkaido University
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中山 仁
北大薬
関連論文
- Synthesis of Diazipine and [^3H]Diazipine : Novel dihydropyridines as Photoaffinity Probes of Calcium Channels
- Fluorescence Labeled and Cross-Linked Subtilisin : Kinetic Characteristics and Binding to Streptomyces Subtilisin Inhibitor
- Preparation of Fluorescence-Labeled and Cross-Linked Subtilisin
- Inverse Substrates. IX. Amidinophenyl Esters derived from Amino Acids and Peptides : Synthesis and Properties as Trypsin Substrates
- New Fluorogenic Substrates for Subtilisin
- Synthesis of a New Fluorogenic Substrate for Cystine Aminopeptidase
- Synthesis of a Key Fluorogenic Amide, L-Arginine-4-methylcoumaryl-7-amide (L-Arg-MCA) and Its Derivatives. Fluorescence Assays for Trypsin and Papain
- A New Fluorogenic Substrate for Aminopeptidase
- Comparison of Deacylation Rates of Chymotryptic Catalysis within an Enantiomeric Pair of p-Nitrophenyl Esters
- Multifunctional Cross-Linking Reagents. I. Synthesis and Properties of Novel Photoactivable, Thiol-Directed Fluorescent Reagents
- Pyranine Phosphate as a New Fluorogenic Substrate for Acidic and Alkaline Phosphatases
- Characterization of Saccharide Moiety in the Electroplax Sodium Channel
- PHOTOREACTION OF N-2-ALKENYLTHIOPHTHALIMIDES : 1,4-DITHIANE FORMATION BY INTRA- AND INTERMOLECULAR TWO-FOLD PHOTOREACTIONS AND THE X-RAY ANALYSIS OF THE DITHIANES
- INTRAMOLECULAR PHOTOCYCLOADDITION OF 3-SUBSTITUTED DITHIOSUCCINIMIDES : FACILE SYNTHESIS AND THE CRYSTAL STRUCTURE OF HIGHLY STRAINED MULTICYCLIC FUSED THIETANE SYSTEM
- Syntheses of Nitro-Substituted Aryl Diazirines. An Entry to Chromogenic Carbene Precursors for Photoaffinity Labeling
- Photoaffinity Labeling of the Electroplax Sodium Channel with a Photoreactive μ-Conotoxin Carrying a Radioactive and Chromogenic Diazirine
- 1991年度ノ-ベル医学・生理学賞--イオンチャンネル研究の画期的手法を開発
- 膜電位依存性イオンチャンネル
- Photoaffinity Labeling of the Electroplax Sodium Channel with Tetrodotoxin Derivatives. II. : Comparison of the Photoreactivity of Different Photoactivable Group in the Tetrodotoxin Binding Site
- Synthesis of μ-Conotoxin GIIIA : A Chemical Probe for Sodium Channels
- タンパク質の構造と機能解析のための有機試薬--光アフィニティラベル試薬の設計と応用 (「バイオサイエンスを支える蛋白質の化学」特集号)
- Photoaffinity Labeling of a δ-Receptor Component of NG 108-15 Cells with a New Enkephalin Analog(Biological)
- イオンチャンネル--Na+チャンネル分子の化学構造を中心にして (レセプタ-の化学)
- カルシウムチャンネル分子 (1987年の化学-2-)
- THE PHOTOAFFINITY LABELING WITH A TETRODOTOXIN DERIVATIVE OF A SODIUM CHANNEL PROTEIN FROM THE ELECTRIC EEL
- 分子としてのナトリウムチャンネル
- 大きく展開するか分子レベルのNaチャンネルの研究 (1985年の化学)
- 化学からみた生体の情報と応答の接点--レセプタ-
- モルヒネ様薬理作用を示すオピオイドペプチド研究の進歩 (1982年の化学-2-)
- 光親和性標識試薬の設計と応用
- The Norrish Type II Reaction of Thiophthalimides Having a Benzylic Hydrogen in an N-Alkyl Side Chain
- Introduction of γ-Glutamyl Residue into Chymotrypsin and Agarose Gel : Application to Cross-Linking and Immobilization of Protein
- Dansylation of Streptomyces Subtilisin Inhibitor : Spectrometric Analysis of the Fluorescence-Labeled Inhibitor
- Schiff Base Copper(II) : Chelate as a Tool for Immobilization of Protein
- Diketene Analogs as β-Lactamase Inhibitor
- Synthesis and Physicochemical Properties of Cyclic Peptides
- Comparative Studies on the Stability of Acyl Enzyme Intermediates : An Approach to the Design of Temporary Inhibitors for Trypsin-like Enzymes
- Bimane Fluorogenic Substrates for Microdetermination of Angiotensin Converting Enzyme Level in Serum
- Novel Fluorogenic Substrates for Phosphodiesterase I
- New Fluorogenic Substrates for Microdetermination of Cathepsin C
- Photochemistry of Conjugated Nitrogen-Thiocarbonyl Systems. VII. : Photoaddition of Quinoline-, Isoquinoline- and Phthalazine-Thione Systems to Olefins
- 生体機能解明のための化学合成
- ペプチド性貝毒コノトキシン--イオンチャンネル研究への化学的プロ-プ (1990年の化学-2-)
- Novel Fluorogenic Substrates Containing Bimane System for Microdetermination of Angiotensin I Converting Enzyme
- 受容体の光親和性標識--リガンド結合部位の決定 (1989年の化学-2-)
- Photochemistry of Conjugated Nitrogen-Thiocarbonyl Systems. VI. : Photoaddition of Olefins to 2-Thiouracil and 2-Thioquinazolin-2,4-(1H, 3H)-dione
- New Fluorogenic Substrates for Microdetermination of Carboxypeptidase A
- New Water-Soluble Fluorogenic Amine. : 7-Aminocoumarin-4-methanesulfonic Acid (ACMS) and Related Substrates for Proteinases
- イオンチャンネルの化学構造--光親和性標識法によるアプロ-チ (1988年の化学-2-)
- Efficient Synthetic Method for Ethyl (+)-(2S,3S)-3-[(S)-3-Methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl]-2-oxiranecarboxylate (EST), a New Inhibitor of Cysteine Proteinases(Medicinal Chemistry,Chemical)
- Photochemistry of Conjugated Nitrogen-Carbonyl Systems. III. : Photosensitized Oxygenation of 3-and 6-Substituted 2-Pyridones(Organic,Chemical)
- INTRAMOLECULAR PHOTOCYCLIZATION OF 3-SUBSTITUTED ALICYCLIC DITHIOIMIDES : FACILE SYNTHESIS OF 2-AZABICYCLOALKANES VIA THE NORRISH TYPE II PROCESS
- イオンチャンネルのイオン選択性を決める構造部
- イオンチャンネル機能部位の構造 (1993年の化学-6-)
- 細胞機能とイオンチャンネルの分子構築 (1991年の化学-7-)
- Photo-Affinity Labeling. II. Photolysis of Amido Derivatives of Nitrophenyl Azides
- Photochemistry of Succinimides with a Cycloalkenylalkyl Group in the Side Chain. Competitive Norrish Type II and Paterno-Buchi Reactions
- PHOTO-DEAROMATIZATION. 1,2-PHOTOADDITION OF ALCOHOL TO N, 3-DIMETHYLPHTHALIMIDE WITHOUT PHOTOENOLIZATION
- 分子としてのナトリウムチャンネル
- タンパク質の構造と機能解析のための有機試薬 : 光アフィニティラベル試薬の設計と応用