Rituximab Used Successfully in the Treatment of Anti-NMDA Receptor Encephalitis
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概要
- 論文の詳細を見る
We report the case of a young woman with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, without tumor, who was successfully treated with rituximab. Because conventional immunotherapy, including corticosteroids, immunoglobulin (IVIg), and plasma exchange showed little improvement in our patient, we introduced another treatment using rituximab. A week after the first administration of rituximab, her symptoms improved gradually and significantly. This case provides in vivo evidence that rituximab is an effective agent for treating anti-NMDAR encephalitis, even in those cases where conventional immunotherapies have been ineffective. Rituximab should be regarded as a beneficial therapeutic agent for this disease.
- 社団法人 日本内科学会の論文
著者
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Hino Shuji
Department Of Material And Biological Chemistry Faculty Of Science Yamagata University
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Takeda Takahiro
Department Of Bioengineering And Robotics Tohoku University
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Yamamoto Kenji
Department Of Cardiovascular Surgery Kanagawa Cardiovascular And Respiratory Center
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Shibata Noriyuki
Department Of Pathology School Of Medicine Tokyo Women's Medical University
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Shibuya Koichi
Department of Neurology, Saitama Red Cross Hospital, Japan
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Shibuya Koichi
Department of Chemistry, Faculty of Science, Okayama University
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Ikeguchi Ryotaro
Department of Neurology, Saitama Red Cross Hospital, Japan
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Akiyama Shigeo
Department of Neurology, Saitama Red Cross Hospital, Japan
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Kubo Hiromasa
Department of Neurology, Saitama Red Cross Hospital, Japan
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Hino Shuji
Department of Neurology, Saitama Red Cross Hospital, Japan
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