Effect of physical exercise on lipolysis in white adipocytes

スポンサーリンク

概要

• 論文の詳細を見る

• Fatty acids are derived from the hydrolysis of triacylglycerol (TG) found in white adipose tissue, muscle tissue and circulating lipoproteins. The mobilization of free fatty acids (FFA) from white adipose tissue contributes to about 50% of the FFA utilized during moderate-intensity exercise. The delivery of FFA from white adipose tissue is improved by hormone-stimulated lipolytic events in white adipocytes (WA). Thus, the lipolysis in WA that provides fuel for metabolism has been a highly conserved function throughout the course of evolution. This short review outlines our current understanding of the molecular regulation of TG lipases via the lipolytic cascade in WA, as well as provides an account of our recent findings concerning changes in the lipolytic molecules of WA that result from acute and habitual exercise.

著者

• SAKURAI Takuya

  Department of Molecular Predictive Medicine and Sport Science, Kyorin University, School of Medicine

• Izawa Tetsuya

  Department Of Exercise And Sport Science Graduate School Of Science Tokyo Metropolitan University

• OGASAWARA Junetsu

  Department of Kinesiology, Graduate School of Science, Tokyo Metropolitan University

• Nakano Norihiko

  Aino Institute Of Regeneration And Rehabilitation Aino University

• TAKAHASHI Kazuto

  Third Department of Internal Medicine, Kyorin University, School of Medicine

• Takahashi Kazuto

  Third Department Of Internal Medicine Kyorin University School Of Medicine

• Ohno Hideki

  Department Of Gastroenterology Graduate School Of Medicine University Of Tokyo

• Toshinai Koji

  Neurology Respirology Endocrinology And Metabolism Division Of Internal Medicine University Of Miyaz

• Ishida Hitoshi

  Third Department Of Internal Medicine Kyorin University School Of Medicine

• Kizaki Takako

  Department Of Molecular Predictive Medicine And Sport Science Kyorin University School Of Medicine

• Izawa Tetsuya

  Department of Sports Biochemistry, Faculty of Health and Sports Science, Doshisha University

• Sakurai Takuya

  Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, 4-17-1 Wakasato, Nagano 380-8553, Japan

• OHNO Hideki

  Department of Gastroenterology and Cancer Gene Regulation, Kanazawa University Graduate School of Medical Sciences

関連論文

• Is Angiotensin I-Converting Enzyme I/D Polymorphism Associated with Endurance Performance and/or High Altitude Adaptation ?
• Supplementation of Antioxidants Prevents Oxidative Stress during A Deep Saturation Dive
• 2B-O-1 The mechanisms underlying prolonged exercise training : induced alterations in levels of adipose triglyceride lipase (ATGL) in rat primary adipocytes(The Proceedings of the 18th Annual Meetings of Japan Society Exercise and Sports Physiology Jury 3
• 1A-20 Effects of tumor necrosis factor-α and nitric oxide on several genes in rat adipocytes(Sports Biochemistry, The Proceedings of the 13th Annual Meetings of Japan Society of Exercise and Sports Physiology July 30-31, (Tokyo))
• Relationship between eradication therapy and clarithromycin-resistant Helicobacter pylori in Japan
• Exercise Training Enhances Tumor Necrosis Factor-α-Induced Expressions of Anti-Apoptotic Genes without Alterations in Caspase-3 Activity in Rat Epididymal Adipocytes
• Primary biliary cirrhosis associated with type A gastritis and chronic thyroiditis
• Effect of Eccentric Exercise on Neutrophil Function in Human Plasma
• Physical Exercise and Extracellular Superoxide Dismutase:Antiatherogenic Effects
• Changes in Nitric Oxide and Inducible Nitric Oxide Synthase Following Stretch-Induced Injury to the Tibialis Anterior Muscle of Rabbit
• Effect of Different Intensity and Duration of Exercise with the Same Total Oxygen Uptake on Lipid Peroxidation and Antioxidant Enzyme Levels in Human Plasma
• Pancreatic Endocrine Function and Glucose Transporter (GLUT)-2 Expression in Rat Acute Pancreatitis
• 2-P-34 The possible mechanisms underlying acute exercise-induced alterations in lipolysis in rat primary adipocytes(The Proceedings of the 17th Annual Meetings of Japan Society of Exercise and Sports Physiology Jury 25-26, (Tokyo))
• 1-O-12 Exercise training suppresses adipogenesis of adipose tissue-derived stem cells(The Proceedings of the 17th Annual Meetings of Japan Society of Exercise and Sports Physiology Jury 25-26, (Tokyo))
• Swimming Training Prevents Induction of Suppressor Macrophages in Mice during Acute Exposure to Cold
• The Supplementation of Oligonol, the New Lychee Fruit-derived Polyphenol Converting into a Low-molecular Form, Has a Positive Effect on Fatigue during Regular Track-and-field Training in Young Athletes
• 4. Oxidative stress in rat white adipose tissue is decreased by exercise training(The Proceedings of the 15th Annual Meetings of Japan Society of Exercise and Sports Physiology July 26-27, (Hirosaki))
• Functional roles of Fli-1, a member of the Ets family of transcription factors, in human breast malignancy
• Gliclazide Inhibits Proliferation but Stimulates Differentiation of White and Brown Adipocytes
• 1A-10 Down-regulation of β_2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation(Immunology and Endocrinology, The Proceedings of the 13th Annual Meetings of Japan Society of Exercise and
• 1A-19 Effect of acute exercise on the expressions of Bax and BCL gene in rat adipocytes(Sports Biochemistry, The Proceedings of the 13th Annual Meetings of Japan Society of Exercise and Sports Physiology July 30-31, (Tokyo))
• 1B-03 Effect of exercise training on tumor necrosis factor-α-induced expressions of lipogenic genes in rat adipocytes(Sports Biochemistry, The Proceedings of the 13th Annual Meetings of Japan Society of Exercise and Sports Physiology July 30-31, (Tokyo))
• 1B-02 Acute exercise induces alteration in β-adrenergic receptor-cAMP signal transduction system via ubiquitin-pro-teasome proteolysis pathway in rat adipocytes(Sports Biochemistry, The Proceedings of the 13th Annual Meetings of Japan Society of Exercise
• 1D08 The effect of exercise training and nitric oxide on the glucose-stimulated insulin secretion
• 3P14:The effect of exercise-training on the generation of nitric oxide in pancreatic islet of Langerhans
• 3P11:Effect of single bout exercise on adipocyte lipolysis(II)
• 2B-04 Temporal change of PGC-1α protein expression and oxidative capacity to endurance exercise in mouse skeletal muscles(Muscular Function, The Proceedings of the 13th Annual Meetings of Japan Society of Exercise and Sports Physiology July 30-31, (Tokyo)
• Effects of Intensity and Duration of Endurance Exercise on Skeletal Muscle Fiber Type Transition in Mice
• The experimental system to analyze mRNA expression profiles between slow and fast muscle fibers
• We have two strategies to attain healthy aging
• Effect of Hyperventilation During Resistance Exercise on Hormonal Response in Humans
• Hematological Responses in Juveniles after Training at Moderate Altitude
• Induction of MIC1P1 mRNA in rat skeletal muscle indicates the activation of the calcineurin signaling pathway during exercise
• 2Q05 Changes in the activity-level of the cerebral cortex-the function of concentration maintenance (TAF) and influence of the exercise in the elderly
• 1Q07 Effect on blood adipose tissue and MDA-LDL with combined exercise training in middle-aged and older persons
• 2P29 Effects of Exercise Intervention on Physical Fitness and Health for Physically Independent Elderly : A Randomized Controlled Trial
• 1P14 Effects on muscle oxygenation of exercise program in older persons
• 1C01 Nobel method for the identification of oxidative fibers in skeletal muscle
• 2ME:Exercise Training and Immune Function
• Physical Exercise and Uncoupling Protein Family
• 1AD4 Effect of MAF on mitochondrial energy metabolism in C2C12 cultured myotubes(The Proceeding of the 14th Annual Meeting of Japan Society of Exercise and Sports Physiology July 29-30, (Hiroshima))
• 1D09 Effect of an acute exercise on the β-adrenergic receptor-adenylate cyclase system in rat adipocytes
• Morphological Evolution during Isothermal Crystallization Observed in a Crystalline-Crystalline Diblock Copolymer
• Disposition of protein-bound 3-nitrotyrosine in rat plasma analysed by a novel protocol for HPLC-ECD
• Application of Microdialysis Techniques for the Study of Exercise and Environment Physiology
• Molecular cloning, and characterization and expression of dihydrolipoamide acetyltransferase component of murine pyruvate dehydrogenase complex in bile duct cancer cells
• The Synergistic Effect of Dietary Calcium Restriction and Exhaustive Exercise on the Antioxioxidant Enzyme System in Rat Heart
• O-9 Effect of hyperventilation during resistance exercise on muscle oxygenation and hormonal response in humans(The Proceedings of the 12th Annual Meetings of Japan Society of Exercise and Sports Physiology)
• Cardiac Output and Stroke Volume at Anaerobic Threshold During Walking Exercise in Healthy Aged Subjects
• 3P23:Effects of a community-based exercise program on the physical function and daily functional capacity of older persons of varying fitness levels
• 1P27:Effect of leg muscular strength and walking ability on health promotion exercise in elderly women
• Reactive Oxygen Species (ROS) and Exercise : 2SB1:The Present State and Future Development of the Research for Reactive Oxygen Species (ROS) and Physical Exercise
• Efficacy of Clostridium butyricum preparation concomitantly with Helicobacter pylori eradication therapy in relation to changes in the intestinal microbiota
• Analysis of Combined Full Energy Peaks of Gamma-Ray Spectra
• Up-Regulation of JAM-1 in AR42J Cells Treated with Activin A and Betacellulin and the Diabetic Regenerating Islets
• Effect of Acute Exercise on ANP-Induced Inhibition of Aldosterone Release in Rat Adrenals
• Stress- and Aging-Associated Modulation of Macrophage Functions
• 242 Effect of community-based exercise program on the physical fitness and mental health of obese older women
• 128 Exercise Tolerance Capacity on Treadmill Walking in The Older Persons
• 2C-05 Effect of mild aerobic exercise training on blood coagulability and fibrinolytic activity in middle- and old-aged obese females
• 2MF:Exercise and Lipolysis
• (E40911) Relationship between muscle oxygenation obtained from the arterial occlusion with maximal work intensity and aerobic capacity
• Acute or Chronic Exercise Alters Angiotensin II-Induced Contraction of Rat Aorta
• Possible Role of Nitric Oxide on Adipocyte Lipolysis in Exercise-Trained Rats
• Effects of health and physical fitness classes for older adults on cardiorespiratory fitness and functional capacity
• The Effect of Endurance Training on Secreting Adipocyokine
• The Effect of Endurance Training on A-kinase Subtypes in Adipocyte
• Longitudinal Change in the Physical Performance of Older Adults in the Community
• Oxidative Metabolism in Skeletal Muscle Measured During Supramaximal Exercise in Sprinter and Active Control Groups by Near Infrared Continuous Wave Spectroscopy
• Antioxidative Effects of a New Lychee Fruit-Derived Polyphenol Mixture, Oligonol, Converted into a Low-Molecular Form in Adipocytes
• 〈Reviews〉Physiological Science of Leptin : Recent Findings
• Relation between Fat Distributions and Several Plasma Adipocytokines after Exercise Training in Premenopausal and Postmenopausal Women
• The relationships between fat distribution and plasma adipocytokines(Leptin, PAI-1) : the effects of exercise training
• 1F3:Influence of exercise training on the insulin secretion by cathecholamines
• Clinical aspects of the central pattern generator in the human spinal cord
• A novel hypothalamic peptide, neuroendocrine regulatory peptide-2, regulates feeding behavior via the orexin system in the hypothalamus
• Significant increase in the melting temperature of poly(ε-caprolactone) blocks confined in the crystallized lamellar morphology of poly (ε-caprolactone)-block-polyethylene copolymers
• Adult stem cell transplantation for the treatment of spinal cord injury
• Degenerative and of regenerative changes in the dorsal funiculus of the cryoinjured spinal cord of rats : electron microscopic study
• Enhanced Release of Monocyte Chemoattractant Protein-1 (MCP-1) by High Glucose and Free Fatty Acid and its Underlying Mechanism in MIN6 β cells
• Choroid plexus : with special reference to neuroprotective function
• Effect of exercise on HIF-1 and VEGF signaling
• Effect of physical exercise on lipolysis in white adipocytes
• Recent advances in the adaptations of adipose tissue to physical activity: Morphology and adipose tissue cellularity
• The effects of exercise on macrophage function
• Formation of the 1.014 eV Photoluminescence Cu Center in Cu-implanted Silicon Crystals and the Center’s Model
• Effects of exercise on the hexosamine biosynthetic pathway and glycosylation
• Effects of β2-agonists and exercise on β2-adrenergic receptor signaling in skeletal muscles
• Influence of mitochondrial DNA 5178 C/A polymorphism on serum cholesterol changes : a short-term follow-up in middle-aged Japanese men
• Exercise training and the promotion of neurogenesis and neurite outgrowth in the hippocampus
• Preventive and improvement effects of exercise training and supplement intake in white adipose tissues on obesity and lifestyle-related diseases
• Growth and characterization of SiC films by hot-wire chemical vapor deposition at low substrate temperature using SiF4/CH4/H-2 mixture
• Relationship between compliance with ophthalmic examinations preoperatively and visual outcome after vitrectomy for proliferative diabetic retinopathy
• Effects of Ca2+ and calmodulin antagonists on the oxygen uptake induced by acetylcholine or substance P in rat submandibular gland slices.
• Mechanism of Isoprenaline-Stimulated Diacylglycerol Formation in Rat Parotid Acinar Cells.
• The synthesis of highly strained buttaflanes with aromatic rings.
• Exercise and oxidative stress in hypoxia
• Exercise training and the promotion of neurogenesis and neurite outgrowth in the hippocampus
• The effects of exercise on macrophage function
• Effect of physical exercise on lipolysis in white adipocytes

もっと見る 閉じる

スポンサーリンク