Exercise training and the promotion of neurogenesis and neurite outgrowth in the hippocampus
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概要
- 論文の詳細を見る
There is a developing consensus that physical exercise is useful as a preventive strategy for cognitive impairment found in patients with dementia, particularly those affected by Alzheimer's disease. Many reports state that the exercise-induced improvement of cognitive performance is an enhanced expression of a brain-derived neurotrophic factor and adult neurogenesis in the hippocampus, which is an area of the brain that is important for learning and memory. The process of adult hippocampal neurogenesis consists of the proliferation of neural progenitor cells (NPCs) and neural differentiation and maturation involving the neurite (axons and dendrites) extension of NPCs. Exercise training is well known as a promoter of cell proliferation and survival in the hippocampus; however, little is known about the effects of exercise training on neurite outgrowth in the hippocampus. This review presents the effect of exercise training on neurogenesis and neurite outgrowth in the hippocampus.
- The Japanese Society of Physical Fitness and Sports Medicineの論文
著者
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KIZAKI Takako
Department of Molecular Predictive Medicine and Sport Science, Kyorin University, School of Medicine
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SAKURAI Takuya
Department of Molecular Predictive Medicine and Sport Science, Kyorin University, School of Medicine
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OGASAWARA Junetsu
Department of Kinesiology, Graduate School of Science, Tokyo Metropolitan University
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Akagawa Kimio
Department Of Cell Physiology Kyorin University School Of Medicine
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Fujiwara Tomonori
Department Of Physiology Kyorin University School Of Medicine
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Ohno Hideki
Department Of Gastroenterology Graduate School Of Medicine University Of Tokyo
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Radak Zsolt
Research Institute Of Sport Science Faculty Of Physical Education And Sport Science Semmelweis Unive
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Kizaki Takako
Department Of Molecular Predictive Medicine And Sport Science Kyorin University School Of Medicine
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Ishibashi Yoshinaga
Department Of Molecular Predictive Medicine And Sport Science Kyorin University School Of Medicine
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Izawa Tetsuya
Faculty of Health and Sport Science, Doshisha University
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Akagawa Kimio
Department of Cell Physiology, Kyorin University, School of Medicine
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Fujiwara Tomonori
Department of Cell Physiology, Kyorin University, School of Medicine
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Ogasawara Junetsu
Department of Molecular Predictive Medicine and Sport Science, Kyorin University, School of Medicine
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Sakurai Takuya
Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, 4-17-1 Wakasato, Nagano 380-8553, Japan
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OHNO Hideki
Department of Gastroenterology and Cancer Gene Regulation, Kanazawa University Graduate School of Medical Sciences
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