鼻アレルギ-10年間の臨床集計-2-血清total IgE量と臨床所見

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Serum IgE values were examined in 366 patients with allergic rhinitis with/without bronchial asthma or allergic dermatitis.The patients consisted of 270 cases of allergic rhinitis (Group I), 71 with rhinitis and bronchial asthma (Group II), 9 with three of them (Group III) and also 16 with bronchial asthma.The serum IgE level was more than 500IU/ml in 49.3 per cent of Group I, and the mean value was 783.7IU/ml (SD 840.1), while that was 74.6 per cent of Group II with a mean of 1769.0IU/ml (SD 1474.9).The elevated IgE value was insignificant in the case of Group I, but Group II and III had significantly high IgE levels.Patients aged from eleven to fifteen had a higher IgE level (1389.9IU/ml, SD 1074.0) than other ages in Group I, but the IgE level in Group II was not related to any age groups.The serum IgE level was not related to sex or the type of allergens, and had no influence upon the degree of eosinophilia or the responsiveness to the provocative nasal test.In only three per cent of Group I the serum IgE level was over 3, 000IU/ml. A patient with elevated IgE over 3, 000IU/ml has a possibility of having an other allergic disease in addition to rhinitis, or the person may develop other disease besises allergic rhinitis in the future.
耳鼻咽喉科臨床学会の論文