右口角部に発性した血管肉腫の1例

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A 44-year-old male had a rapidly enlarging tumor at the right angle of his mouth. By means of the light and electron microscopic observation, we diagnosed the case as angiosarcoma. The lesion was irradiated with 6, 000 rads and excised sufficiently.Under the light microscope, spindle- or oval-shaped tumor cells with atypical, round, clear nuclei and a clear nucleolus proliferated like a network. Several tumor cells were surrounded by silver fibers. Under the electron microscope, pinocytotic vesicles were seen to be numerous. Fine cytoplasmic filaments, Golgi apparatus, and rough endoplasmic reticulum were seen in great abundance. Desmosome, fingerbinding, and the cellular processes were also seen. Based on the above findings, we made a diagnosis of angiosarcoma.Angiosarcoma is relatively rare, and is very rare in the soft tissue as in this case.
耳鼻咽喉科臨床学会の論文