顔面に発生したaggressive fibromatosisの1例

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A 8-month-old male infant, who presented with a rapidly-growing tumor of 3×2cm in the left side of the external nose, was reported. This tumor was elastic, hard, non-tender, not fluctuating and the overlying skin was normal. The tumor was adherent to the surrounding tissue.On laboratory examination, CPK (729ml.U./ml) and aldolase (5.7mU./ml) were significantly elevated.Encephalocele was ruled out, because the tumor was not expansive, did not compress the jugular veins and had no connection with the brain on CT-Scanning.The entire tumor was surgically removed with the surrounding tissue. His postoperative course was uneventful.Pathological examinations (light microscopic and electronmicroscopic) revealed the tumor to be fibromatosis of the aggressive type. We speculated that the elevation of CPK and aldolase was due to surrounding muscle degeneration caused by fibromatosis.
耳鼻咽喉科臨床学会の論文