日本における非定型抗酸菌感染症の研究 (国療非定型抗酸菌症共同研究班1980年度報告) : <I>Mycobacterium kansasii</I> 痒のEndemic StatusからEpidemic Statusへの変化

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From data obtained in 1980, the incidence rate of the lung disease due to atypical mycobacteria in Japan was estimated as 1.5 per 105 population per year. The incidence rate during the period from 1976 to 1980 ranged from 1.3 to 1.9 per 105 population per year, and the rate seemed almost constant.<BR>When observed on individual diseases, however, the incidence rate of the lung disease due to M. avium-M. intracellulare, which occupies a majority of all atypical mycobacteriosis, ranged from 1.2 to 1.7 per 105 population per year and seemed to be almost constant, whereas the prevalence rate of the lung disease due to M. kansasii increased from 0.04-0.1 in 1975-1976 to 0.25 in 1980. In accordance with the increase of the incidence rate of the M. kansasii disease, the location where the disease was found has spread from Tokyo area to several prefectures, Osaka, Fukuoka, Shizuoka and Kochi. To explain this phenomenon, a hypothesis has been presented that the increase of the incidence correlates to decrease of tuberculosis. In a circumstance where the prevalence of tuberculosis is still high, persons with attenuated resistance may be infected by tubercle bacilli and develop tuberculosis, but in a cir cumstance where the prevalence of tuberculosis is low, such persons may become infected by M. kansasii which originates from the environment.<BR>In the past one decade, 35, 696 patients were hospitalized to our tuberculosis departments. Out of these patients, 632 (1.8%) of the patients with atypical mycobacteriosis were found; M. kansasii disease, 59 (9.3%); M. szulgai disease, 3 (0.5%); M. avium-M. intracellulare disease, 558 (88.3%); M. fortuitum disease, 7 (1.1%); M. chelonei disease, 3 (0.5%); others, 2 (0.3%).
日本結核病学会の論文

日本における非定型抗酸菌感染症の研究 (国療非定型抗酸菌症共同研究班1980年度報告) : <I>Mycobacterium kansasii</I> 痒のEndemic StatusからEpidemic Statusへの変化

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