国立療養所中部病院で分離された非定型抗酸菌の菌種および分離頻度 (1972-1976年の5年間の観察)

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Monthly sputum examinations were carried out on patients hospitalized in the National Chubu Hospital during the period of 5 years (January 1972 to December 1976), and all acid-fast organisms isolated were identified. 1. The prevalence rate of acid-fast organisms other than tubercle bacilli, including Gordona (Rhodochrous complex) and Nocardia, among all acid-fast organisms ranged from 5.6 to 14.8% and differed from year to year (Table 1). Background-prevalence rate (prevalence rate of acid fast organisms other than tubercle bacilli, after subtracting those which have caused disease in patients, among all acid-fast organisms) ranged from 2.5 to 9.5% (Table 2). Accordingly, annual changes in the background-prevalence rate seems to exist. These changes might be explained most probably by changes of ecology of acid-fast organisms in environment. 2. Background-prevalence rate (casual isolation-rate) in various months of five years was shown in Table 3. The rate was high from January to March and low from April to October. Increase of the rate in winter season was probably due to changes in clearance of respiratory tract of patients. 3. The kind of species was shown in Table 4. The distribution of the species was similar to the results obtained by the National Chest Hospital Group. Comparison between the results in this hospital and those in the National Tokyo Chest Hospital, which were confirmed by us, was shown in Table 5. A marked difference was present in the rate of M. kansasii. 4. The kind of species of casual isolates was shown in Table 6. The background-prevalence rate of M. avium-intracellulare complex was 0.4%. This rate will be served as a standard for considering whether or not an isolation frequency from a patient belongs to a normal range. A total of 539 strains of acid-fast organisms other than tubercle bacilli were isolated. Out of these, 235 strains were isolated from 26 patients who were considered to have lung disease due to these organisms, and other 304 strains were isolated from 255 patients as casualisolates. The mode of excretion of these casual isolates was shown in Table 7.
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国立療養所中部病院で分離された非定型抗酸菌の菌種および分離頻度 (1972-1976年の5年間の観察)

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