Tween80による遅発育性Mycobacterium intracellulareの発育促進

概要

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In the course of the co-operative study with thirteen National Sanatoria on the infection of atypical mycobacteria, 277 strains of mycobacteria received from various hospitals were identified as Mycobacterium intracellulare. Among these strains of M. intracellulare, 15 strains (5.4%) showed very dysgonic growth on the Ogawa egg medium as well as on the Sauton agar. In contrast to the other strains of M. intracellulare that showed good growth on a modified Sauton agar, in which sodium glutamate was substituted for asparagine, these 15 strains showed no growth or, if any, very scant growth on the Sauton agar. Unlike the other strains of M. intracellulare, these slowly growing strains were unable to grow on synthetic media containing various nitrogen compounds as the sole source of nitrogen. The growth of these slowly growing strains of M. intracellulare was enhanced greatly by addition of Tween 80 (final concentration of 1%) to the Sauton agar.
日本結核病学会の論文