Mycobacterium tuberculosis, M. africanum, M. bovisおよびM.mimtiの関係についての計数分類学的解析

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A numerical analysis using 88 characters was carried out on 40 strains received as Mycobacterium tuberculosis, M. africanum, M. bovis, and M. microti (Tables 1 and 2). The clustering was made by single-linkage method. The results showed that all 40 strains formed a cluster at a level of 95% of the matching coefficient (Fig. 1). Within this cluster, a subcluster consisting of M. tuberculosis strains, a subcluster consisting of M. africanum strains and M. bovis strains, and a subcluster consisting of M. mic roti strains could be distinguished, but a considerable number of M. bovis strains did not belong to any subcluster. The results obtained in the study supported Tsukamuras proposal that M. tuberculosis and M. bovis should be combined into one species, M. tuberculosis, the present names of the taxa being reduced to two subspecies, subsp. tuberculosis and subsp. bovis (Tsukamura, M.: Tubercle, 48: 311, 1967). In view of the results, M. africanum is considered to be a variety of M. bovis. M. microti is closely related to M. bovis, but it is differentiated from M. bovis by its positive niacin production and positive nicotinamidase and pyrazinamidase activities (Tables 3 and 4). (The authors express their appreciation to Prof. H.H. Kleeberg, Tuberculosis Research Institute, Pre toria, South Africa, for his kind supply of many strains used in the present study and for his permission of the publication of the study, in which his strains have been used.)
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<I>Mycobacterium tuberculosis, M. africanum, M. bovis</I>および<I>M.mimti</I>の関係についての計数分類学的解析

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