Myrseguinosides A—E, Five New Glycosides from the Fruits of Myrsine seguinii

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概要

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• Chemical investigation of the 1-BuOH soluble fraction of the dried fruits of Myrsine seguinii (Myrsinaceae) led to the isolation of five new glycosides, named myrseguinosides A—E (1—5), together with eight known compounds (6—13). The absolute structures of the new glycosides were elucidated by spectroscopic and chemical analyses to be a monoterpene glucoside (1), two flavonol glycosides (2, 3), and two oleanane-type triterpene saponins (4, 5). Myrseguinosides B (2), D (4), and E (5) exhibited 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity and growth inhibitory activity toward human cancer cells, respectively.

著者

• Matsunaga Keiji

  Graduate School Of Pharmaceutical Sciences Kyoto University

• Matsunami Katsuyoshi

  Department of Pharmacognosy, Graduate School of Biomedical Sciences, Hiroshima University

• Takeda Yoshio

  Fac. Of Pharmacy Yasuda Women's Univ. 6-13-1 Yasuhigashi Asaminami-ku Hiroshima 731-0153 Jpn

• Takeda Y

  Okinawa Prefectural Experimental Station Of Forestry

• Takaishi Y

  Univ. Tokushima Shomachi Jpn

• Otsuka Hideaki

  Division Of Medicinal Chemistry Graduate School Of Biochemical Sciences Hiroshima University

• Otsuka Hideaki

  Department Of Pharmacognosy Graduate School Biomedical Sciences Hiroshima University

• Takaishi Y

  Graduate School Of Pharmaceutical Sciences University Of Tokushima

• Kawahata Masatoshi

  Fac. Of Pharmaceutical Sciences Tokushima Bunri Univ. Kagawa Campus

• Matsunaga Kazuhisa

  Faculty Of Pharmaceutical Sciences Fukuoka University

• Takeda Yoshio

  Faculty Of General Arts And Sciences The Tokushima University

• Matsunaga K

  Faculty Of Pharmaceutical Sciences Fukuoka University

• Takeda Y

  Daiichi Pharmaceutical Co. Ltd. Tokyo Jpn

• Otsuka H

  Hiroshima Univ. Hiroshima Jpn

• Matsunami Katsuyoshi

  Department Of Pharmacognosy Graduate School Biomedical Sciences Hiroshima University

• Takeda Yoshio

  Faculty of Pharmaceutical Sciences, Yasuda Women's University

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