Immunosuppressive Sesquiterpenes from Tripterygium wilfordii

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概要

• 論文の詳細を見る

• Five new sesquiterpenes, 1β-furanoyl-2β, 3α, 7α, 8β, 11-pentaacetoxy-4α, 5α-dihydroxy-dihydroagarofuran (1), 1β, 2β, 3α, 5α, 7β, 8β, 11-heptaacetoxy-dihydroagarofuran (2), 1β-furanoyl-2β, 3α, 7α, 8β, 11-pentaacetoxy-5α-hydroxy-dihydroagarofuran (3), 1β, 7β, 8α-triacetoxy-2β-furanoyl-4α-hydroxy-11-isobutyryloxy-dihydroagarofuran (4), and 1β-nicotinoyl-2β, 5α, 7β-triacetoxy-4α-hydroxy-11-isobutyryloxy-8α-furanoyl-dihydroagarofuran (5), were isolated from the xylem of Tripterygium wilfordii, together with a known compound (6). Their structures were elucidated on the basis of spectroscopic studies. Compounds 2-5 showed significant immunosuppressive activities.

• 公益社団法人日本薬学会の論文
• 2005-06-01

著者

• Takeda Yoshio

  Fac. Of Pharmacy Yasuda Women's Univ. 6-13-1 Yasuhigashi Asaminami-ku Hiroshima 731-0153 Jpn

• Takaishi Y

  Univ. Tokushima Shomachi Jpn

• TAKAISHI Yoshihisa

  Faculty of Pharmaceutical Sciences, University of Tokushima

• Gao Wenyuan

  The College Of Pharmaceuticals And Biotechnology Tianjin University

• Duan Hongquan

  The College Of Pharmaceuticals And Biotechnology Tianjin University

• Takaishi Yoshihisa

  Faculty Of Pharmaceutical Sciences University Of Tokushima

• Wang Xiaodong

  The College Of Pharmaceuticals And Biotechnology Tianjin University

• Takeda Y

  Daiichi Pharmaceutical Co. Ltd. Tokyo Jpn

• YAO Zhi

  Department of Immunology, Tianjin Medical University

• ZHANG Shaoyu

  The School of Pharmacy, Tianjin Medical University

• ZHANG Yanwen

  The School of Pharmacy, Tianjin Medical University

• DUAN Hongquan

  The School of Pharmacy, Tianjin Medical University

• Yao Zhi

  Department Of Immunology Tianjin Medical University

• Zhang Yanwen

  The School Of Pharmacy Tianjin Medical University

• Zhang Shaoyu

  The School Of Pharmacy Tianjin Medical University

• Takaishi Y

  Faculty Of Pharmacy Yasuda Women's University

• Yao Zhi

  Chemical Engineering & Pharmaceutics Coll. Henan Univ. Of Sci. And Technol.

• Zhang SY

  The School of Pharmacy, Tianjin Medical University

• Zhang YW

  The School of Pharmacy, Tianjin Medical University

• Duan HQ

  The School of Pharmacy, Tianjin Medical University

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