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a-fetoprotein (AFP), al-antitrypin (AAT), ferritin and secretory component (SC) were examined in carcicnoma tissue of hepatocellular carcinoma (HCC) and cholangicocellular carcinoma (CCC) by peroxidase anti-peroxidase methok. AFP was demonstrated in 35.7% of HCC as either granular or inclusion form, but absent in CCC. AAT was more frequent in HCC (92.3%) than in CCC (33.3%), and a variety of the intra-and extracytoplasmic apperarance, such as granular, inclusion, luminal surface and intraluminal secretion form were found in HCC, but only the latter two in CCC. Ferritin was demonstrated as granular form in HCC (57.3%) as well as CCC (33.3%). SC was also found in HCC (57.3%) as well as CCC (83.3%). But, cytoplasmic and inclusion foums were frequent in CCC compared with HCC, in which secretion form was predominant. Sizes and degrees of defferentiation of HCC were not correlated with frequency of above mentioned 4 antigens in carcinoma tissues.
財団法人日本消化器病学会の論文