Stimulation of Immunoreactive Somatostatin Release from Hypothalamic Synaptosomes by High (K<SUP>+</SUP>) and Dopamine
スポンサーリンク
概要
- 論文の詳細を見る
Effects of high (K<SUP>+</SUP>) and dopamine on the release of immunoreactive somatostatin from isolated hypothalamic synaptosomes were studied in rats. High (K<SUP>+</SUP>)(60 mM) and dopamine (10<SUP>-6</SUP> M) in the incubation media stimulated the release of immunoreactive somatostatin and the former effect was completely abolished by the removal of Ca<SUP>++</SUP> from the media. These suggest that hypothalamic somatostatinergic synaptosomes preserved at least one of the important basic properties of secretory cells. Although it is of interest to note that dopamine stimulated the release of somatostatin. Its physiological significance awaits further studies.
- 社団法人 日本内分泌学会の論文
著者
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Demura Hiroshi
Department Of Internal Medicine Institute Of Clinical Endocrinology Tokyo Women's Medical Colle
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Miki Nobuhiro
Department Of Chemistry Graduate School Of Science Tokyo Metropolitan University
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Shizume Kazuo
Department of Internal Medioine Tokyo Women's Medical College
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Demura Reiko
Department Of Environmental Hygiene School Of Pharmacy Hokuriku University
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Wakabayashi Ichiji
Department Of Internal Medicine 3 Nippon Medical School
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MIYAZAWA YUJI
Department of Internal Medicine, Tokyo Womens Medical College
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KANDA MEGUMI
Department of Internal Medicine, Tokyo Womens Medical College
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SHIZUME KAZUO
Department of Endocrinology and Endocrine Research Laboratory Toranomon Hospital
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KANDA MEGUMI
Department of Internal Medicine Tokyo Women's Medical College
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MIYAZAWA YUJI
Department of Internal Medicine, Tokyo Women's Medical College
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