Results of Long-Term Human Growth Hormone Therapy for Pituitary Dwarfism
スポンサーリンク
概要
- 論文の詳細を見る
Since 1961, 14 patients with pituitary dwarfism were treated with human growth hormone (HGH). In this report, the result of long term treatment for more than 2 and a half years in five patients is reported. The dose of HGH was 2-4 mg three times a week. In the first six months, a marked increase in height was observed in all cases. The increase declined gradually and in some cases HGH became almost ineffective. In such cases anti-HGH antibody was observed in the patients blood. Bone age/height age progress ratio was less than one in most cases. No side effect was observed except pain at the site of injection. In two cases, height reached to the level above-2-D of the height of normal adult.
- 社団法人 日本内分泌学会の論文
著者
-
Irie Minoru
Department Of Internal Medicine School Of Medicine Toho University
-
Shizume Kazuo
Department of Internal Medioine Tokyo Women's Medical College
-
MATSUZAKI FUKASHI
Department of Endocrinology and Endocrine Research Laboratory, Toranomon Hospital
-
OSAWA NAKAAKI
Department of Endocrinology and Endocrine Research Laboratory, Toranomon Hospital
-
SHIZUME KAZUO
Department of Endocrinology and Endocrine Research Laboratory Toranomon Hospital
-
IRIE MINORU
Department of Endocrinology and Endocrine Research Laboratory Toranomon Hospital
-
IRIE MINORU
Department of Endocrinology and Endocrine Research Laboratory, Toranomon Hospital
-
MATSUZAKI FUKASHI
Department of Endocrinology and Endocrine Research Laboratory Toranomon Hospital
関連論文
- Growth Hormone (GH) Effects on Central Fat Accumulation in Adult Japanese GH Deficient Patients : 6-month Fixed-dose Effects Persist during Second 6-month Individualized-dose Phase
- Metabolic Effects of Human Growth Hormone Isoform (20k-hGH) in Adults with Growth Hormone Deficiency
- Metabolic Effects of Human Growth Hormone Isoform (20 k-hGH) in Adults with Growth Hormone Deficiency
- Registration System for Growth Hormone (GH) Treatment with Standardized Immunoreactive GH Values in Japan
- Low-dose Growth Hormone Treatment (0.175mg/kg/week) for Short Stature in Patients with Turner Syndrome : Data from KIGS Japan
- Complications in Adults with Growth Hormone Deficiency : A Survey Study in Japan
- The Effect of Growth Hormone Secreted by Mild Exercise on Fatty Acid Mobilization in Patients with Diabetes Mellitus
- MECHANISM OF NATRIURESIS IN PAROXYSMAL SUPRAVENTRICULAR TACHYCARDIA AND THE INFLUENCE OF ATRIAL NATRIURETIC POLYPEPTIDES : Atrial Natriuretic Polypeptide (I) : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Effect of CB-154 Therapy on the Glucose Tolerance, IRI and GH Response to Glucose Administration in Acromegaly
- A Renewal Attempt to Compare the Affinity of Thyroxine-Binding-Globulin To Thyroxine in Normal And Hyperthyroid Sera
- An Attempt to Compare the Affinity of Thyroxine-Binding-Globulin to Thyroxine in Normal and Hyperthyroid Sera
- A Female Case of the HCG-Producing Ectopic Pinealoma Associated with Precocious puberty
- Studies on the Accumulation of Thyroxine in Isolated Bovine Thyroid Cells
- Stimulation of Immunoreactive Somatostatin Release from Hypothalamic Synaptosomes by High (K+) and Dopamine
- Effect of Hypophysectomy on Hypothalamic Somatostatin Content in Rats
- A Case of Isolated Growth Hormone Deficiency Associated with Familial Thyroxine Binding Globulin Deficiency
- Effect of Glipizide on the Release of Insulin in the Perfused Rat Pancreas in vitro
- Effects of Testosterone and Estradiol on Serum Somatomedin A and Growth Rate of Rats
- Degradation of Somatomedin A by Various Organ Homogenates from Rats
- Properties and Concentrations of Somatomedin A in Various Rat Tissues
- Time Course of Distribution to Tissues of 125I -Somatomedin A Injected into the Rat
- Results of Long-Term Human Growth Hormone Therapy for Pituitary Dwarfism
- Long-term Result of Antithyroid Drug Therapy for Graves Disease : Follow up after more than 5 years
- Growth Hormone Response to Hypoglycemia in Puberty and Adolescence
- Reproducibility of Plasma Growth Hormone and Insulin Responses after Double Infusion of Arginine Solution
- Long Term Antithyroid Drug Therapy for Intractable Cases of Graves Disease
- Hypotriglycedemic Action of Synthetic ACTH
- Simultaneous Determinations of Plasma ACTH and GH Levels after an Oral Metyrapone
- Binding Protein of Somatomedin A in Serum from Men and Rats
- A case of histiocytosis X associated with panhypopituitarism and hyperimmunoglobulinemia G and E.
- Treatment of idiopathic pituitary dwarfism with methionyl human growth hormone.
- Short-term study of biosynthesized hGH in man.
- Effect of thyroid hormone on the serum level of somatomedin A.
- Effect of food and GH on the binding of 125I-somatomedin a to the membranes of rat lung and kidney.
- Effect of GH and insulin on the generation of somatomedin by perfused rat liver.
- Induction of specific human growth hormone binding sites in rat liver by human growth hormone.
- Effect of human growth hormone on serum somatomedin A in patients with growth hormone deficiency.