Anti-inflammatory action of progesterone on carrageenin-induced inflammation in rats.
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概要
- 論文の詳細を見る
Effect of progesterone (1 mg/kg) on the inflammation in rats induced by carrageenin was studied. Progesterone inhibited the vascular permeability and the formation of granulation tissue in the early phase of the inflammation. In the chronic proliferative phase, progesterone suppressed the vascular permeability and there was an active resorption of the granulation tissue. Increased degradation of noncollagen protein was observed in the treated group without apparent influence on the metabolism of collagen or on the synthesis of noncollagen protein. The mode of action of progesterone was compared with that of a potent anti-inflammatory steroid, hydrocortisone acetate.
- 公益社団法人 日本薬理学会の論文
著者
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Min Kyung
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Tohoku University
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Tsurufuji Susumu
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Tohoku University
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Nakagawa Hideo
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Tohoku University
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MIN KYUNG
Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tohoku University
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NANJO Kimiko
Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tohoku University
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