CHANGES IN FUNCTIONAL CERULOPLASMIN CONCENTRATIONS OF PLASMA AND EXUDATE AND THE EFFECT OF EXOGENOUS CERULOPLASMIN ON THE CARRAGEENIN-INDUCED INFLAMMATION IN RATS
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概要
- 論文の詳細を見る
Changes in functional ceruloplasmin (Cp) concentrations of plasma and exudate during acute and chronic inflammatory processes were studied in detail by measuring Cp oxidase activity in the carrageenin-induced inflammation in rats. In contrast with the plasma functional Cp level as an acute-phase reactant, the exudate functional Cp level was very low during the acute phase, increased in the chronic phase and reached a constant value which was only half value of the plasma functional Cp level. The locally injected Cp had no effect on the carrageenin-induced inflammation, suggesting that exogenous Cp has no anti-inflammatory effect on the inflamed rats eating normal diet.
- 公益社団法人日本薬学会の論文
著者
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Tsurufuji Susumu
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Tohoku University
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Suzuki Kazuo
Department Of Hamamatsu University School Of Medicine
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Yamaki Kohji
北里大学 薬 薬理
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Yamaki Kohji
Department Of Pharmacology School Of Pharmaceutical Sciences Kitasato University
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NAKAGAWA HIDEO
(Present address) Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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Nakagawa Hideo
(present Address) Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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Suzuki Kazuo
Departmens Of Oral Histology Matsumoto Dental College
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Suzuki K
National Inst. Infectious Diseases Tokyo Jpn
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YAMAKI KOHJI
Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tohoku University
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