INDUCTION OF A DELAYED TYPE HYPERSENSITIVITY TO CARRAGEENIN IN MICE
スポンサーリンク
概要
- 論文の詳細を見る
Induction of a delayed type hypersensitivity to carrageenin in mice was investigated with successful results. Male ddY/s mice were immunized with 1 mg of carrageenin in 100μl of Freund's complete adjuvant-saline (1 : 1) emulsion and challenged 10d after the immunization on their footpads with either 10 or 40μg of the antigen in 2.5μl of Freund's incomplete adjuvant-saline (1 : 1) emulsion. The mice exhibited a strong allergic footpad reaction at 24-48h after the challenge injection. The footpad reaction was successfully transferred with spleen cells. Non-steroidal antiinflammatory drug, indomethacin, and steroidal antiinflammatory drug, dexamethasone, suppressed the delayed type hypersensitivity reaction.
- 公益社団法人日本薬学会の論文
著者
-
Yoshino Shin
Department of Pharmacology, Kobe Pharmaceutical University, Japan
-
Yoshino Shin
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Tohoku University
-
OHUCHI Kazuo
Department of Orthopaedics, Fukushima Medical University
-
TSURUFUJI SUSUMU
Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tohoku University
-
Ohuchi Kazuo
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Tohoku University
-
Tsurufuji Susumu
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Tohoku University
関連論文
- Effect of the C3a-Receptor Antagonist SB 290157 on Anti-OVA Polyclonal Antibody—Induced Arthritis
- Orientational Distribution of Collagen Fibers in the Horizontal Plane of Human Adult Calcaneus
- Anti-estrogenic Activity of Diesel Exhaust Particles
- Pulmonary Emphysema Induced by Cigarette Smoke Solution and Lipopolysaccharide in Guinea Pigs
- EFFECT OF PROTEINASE INHIBITORS HAVING ANTIINFLAMMATORY ACTIVITY ON GELATINASE, ELASTASE AND CATHEPSIN G ISOLATED FROM RAT POLYMORPHONUCLEAR LEUKOCYTES
- Polycyclic Aromatic Hydrocarbons Aggravate Antigen-Induced Nasal Blockage in Experimental Allergic Rhinitis
- A Role of Peripheral Leukocytes in Vascular Permeability and Edema Formation in Air Pouch Type Allergic Inflammation in Rats
- ROLES OF HISTAMINE IN ALLERGIC INFLAMMATION
- INHIBITION OF ALLERGIC FOOTPAD INFLAMMATION BY ANTIRHEUMATIC DRUG D-PENICILLAMINE
- CELLULAR ORIGIN OF CATHEPSIN B IN CARRAGEENIN-INDUCED GRANULOMA TISSUES IN RATS
- PROTEINASE INHIBITORS SUPPRESS THE FORMATION OF GRANULATION TISSUE IN THE CARRAGEENIN-INDUCED INFLAMMATION IN RATS
- Anti-inflammatory effects of Na^+/H^+ exchanger inhibitors
- Intratracheal Sensitization/Challenge-Induced Biphasic Asthmatic Response and Airway Hyperresponsiveness in Guinea Pigs
- THE PREDOMINANCE OF FLUNISOLIDE IN THE TOPICAL USE OF ANTI-INFLAMMATORY STEROIDS
- COMPARATIVE STUDY BETWEEN STEROIDAL AND NONSTEROIDAL ANTI-INFLAMMATORY DRUGS ON THE MODE OF THEIR ACTIONS ON VASCULAR PERMEABILITY IN RAT CARRAGEENIN-AIR-POUCH INFLAMMATION
- INDUCTION OF A DELAYED TYPE HYPERSENSITIVITY TO CARRAGEENIN IN MICE
- Influence of anti-inflammatory and anti-rheumatic drugs on the Th1/Th2 immune system.(GENERAL SESSION BY POSTER PRESENTATION)(IMMUNE AND ALLERGIC SYSTEM)
- ANALYSIS OF THE EFFECT OF AN ANTI-INFLAMMATORY STEROID, DEXAMETHASONE, ON NEUTROPHIL CHEMOTAXIS IN THE BOYDEN CHAMBER WITH A MODIFIED ^Cr-LABELING METHOD
- Complete Dependence on CD4+ Cells in Late Asthmatic Response, but Limited Contribution of the Cells to Airway Remodeling in Sensitized Mice
- Effect of the C3a-Receptor Antagonist SB 290157 on Anti-OVA Polyclonal Antibody-Induced Arthritis
- CONTENTS OF PROSTAGLANDIN E IN THE EXUDATE OF RAT CARRAGEENIN GRANULOMA
- INHIBITION BY HYDROXYUREA OF THE REBOUND OF GRANULOMATOUS INFLAMMATION FOLLOWING WITHDRAWAL OF GLUCOCORTICOID THERAPY
- Analysis of the Mechanism for the Development of Allergic Skin Inflammation and the Application for Its Treatment : Preface
- CHANGES IN FUNCTIONAL CERULOPLASMIN CONCENTRATIONS OF PLASMA AND EXUDATE AND THE EFFECT OF EXOGENOUS CERULOPLASMIN ON THE CARRAGEENIN-INDUCED INFLAMMATION IN RATS
- EFFECT OF COLCHICINE ON CARRAGEENIN-INDUCED GRANULOMATOUS INFLAMMATION IN RATS
- PROINFLAMMATORY ACTIVITY OF COLCHICINE AS REVEALED IN RAT PAW EDEMA METHOD
- DIFFERENCE IN THE ANTI-INFLAMMATORY EFFECT OF INDOMETHACIN BETWEEN ACUTE AND CHRONIC STAGES OF CARRAGEENIN-INDUCED INFLAMMATION
- EFFECT OF METHYLPREDNISOLONE AND "PULSE" THERAPY WITH METHYLPREDNISOLONE SODIUM SUCCINATE ON AUTOLOGOUS IMMUNE COMPLEX NEPHRITIS IN RATS
- CORTISOL-BINDING PROTEIN IN THE CYTOSOL OF RAT CARRAGEENIN GRANULOMA
- Complete Dependence on CD4^+ Cells in Late Asthmatic Response, but Limited Contribution of the Cells to Airway Remodeling in Sensitized Mice
- Anti-inflammatory action of progesterone on carrageenin-induced inflammation in rats.
- Inhibitory effect of a novel anticomplementary agent, K-76COONa, on the release of histamine induced by zymosan and compound 48/80.
- A new simple plastic chemotaxis device of the Boyden chamber type utilizing an immunoassay plate.
- Analysis of the factor(s) involved in pathogenesis of zymosan-induced inflammation in rats.
- Inability of rat anaphylatoxin to induce histamine release in rats.
- The Incorporation Pattern of Glycine and Serine on the Biosynthesis of Collagen and Globin