IMMUNOHISTOCHEMICAL LOCALIZATION OF DIPEPTIDYL PEPTIDASE IV IN RAT DIGESTIVE ORGANS
スポンサーリンク
概要
- 論文の詳細を見る
Immunohistochemical localization of dipeptidyl peptidase (DPP) IV in rat digestive organs was studied using the peroxidase-antiperoxidase (PAP method. In the rat digestive organ observed, a fairly intense immunoreaction of DPP IV was found on the brush border of enterocytes of the small intestine. However, the immunostaining of enterocytes in the small intestine showed marked regional differences. The intensity of the reaction was significantly higher in the jejunum and ileum than in the duodenum. DPP IV was also detected in the cytoplasm of Paneth cells in the jejunum and ileum and on the surface of the crypt epithelium of the colon. In the esophagus, a faint reaction was detected on the surface of the stratified epithelium and connective tissues of the submucosa. DPP IV could not be found in the cells of the stomach by immunohistochemical means. The present results suggest that DPP IV in digestive organs could mainly participate in the final digestion of peptides in which a proline residue is involved.
- 日本組織細胞化学会の論文
著者
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SUZUKI Kazuo
Department of Immunology, Inflammatory Program, Chiba University School of Medicine
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SAHARA Noriyuki
Department of Oral Histology, Matsumoto Dental College
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Sahara N
Matsumoto Dental Coll. Nagano Jpn
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Sahara Noriyuki
Departmens Of Oral Histology Matsumoto Dental College
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Harada Minoru
Oral Biochemistry Matsumoto Dental College
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HARADA Minoru
Department of Mechanical Engineering, Graduate School of Engineering, Yokohama National University
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Suzuki Kazuo
Department Of Hamamatsu University School Of Medicine
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FUKASAWA KATSUHIKO
Oral Biochemistry, Matsumoto Dental College
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FUKASAWA KATSUHIKO
Department of Oral Biochemistry, Matsumoto Dental College
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Harada Minoru
Department Of Mechanical Engineering Graduate School Of Engineering Yokohama National University
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Fukasawa Katsuhiko
Oral Biochemistry Matsumoto Dental College
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Suzuki Kazuo
Departmens Of Oral Histology Matsumoto Dental College
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