A 10-kDa Fragment of Fibronectin Type III Domain Is a Neutrophil Chemoattractant Purified from Conditioned Medium of Rat Granulation Tissue
スポンサーリンク
概要
- 論文の詳細を見る
A neutrophil chemoattractant has been purified from the conditioned medium of granulation tissue obtained from carrageenan-induced inflammation in rats. The purified chemoattractant was a basic protein with a molecular mass of 10 kDa on sodium dodecyl sulfate-polyacrylamide gel electrophoresis(SDS-PAGE)under reducing and non-reducing conditions. NH_2-terminal amino acid sequence of the purified 10-kDa protein was identical with the sequence of rat fibronectin starting from the residue Thr^<585> indicating that the purified 10-kDa chemoattractant is a fragment derived from the NH_2-terminal type III domain of rat fibronectin.
- 公益社団法人日本薬学会の論文
- 2001-07-01
著者
-
TAKANO Katsuhiko
Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharma
-
NAKAGAWA Hideo
Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharma
-
TAKAHASHI Keiji
Shiseido Hospital
-
Nakagawa Hideo
Department Of Physiological Chemistry Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmace
-
Takano K
Department Of Respiratory Medicine And Department Of Clinical Pathology Kanazawa Medical University
-
SHIOTA Satoshi
Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharma
-
Shiota Satoshi
Department Of Physiological Chemistry Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmace
-
Takano Katsuhiko
Department Of Physiological Chemistry Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmace
-
Nakagawa Hideo
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Tohoku University
関連論文
- Serum KL-6, a Novel Mucin-Like Glycoprotein, as an Indicator of Interstitial Pneumonitis Following Lobectomy
- Chemokine Production by Rat Macrophages Stimulated with Streptolysin O from Streptococcus pyogenes
- Role of CXC chemokines in ventilator-induced lung injury in rats
- Mechanical stress on type II alveolar epithelial cells and production of CXC chemokines
- The In Vitro Epithelial Repair Capacity in Acid-Injured Alveolar Cell Model
- Maximal Inspiratory Flow with Nasal Continuous Positive Airway Pressure in Patients with Sleep-Disordered Breathing : Relevance to the Upper Airway Reflex
- Detection of Inspiratory Flow Limitation with Cardiogenic Flow Oscillation in Patients with Obstructive Sleep Apnea
- Beta_1-Adrenergic Agonist Is a Potent Stimulator of Alveolar Fluid Clearance in Hyperoxic Rat Lungs
- EFFECT OF PROTEINASE INHIBITORS HAVING ANTIINFLAMMATORY ACTIVITY ON GELATINASE, ELASTASE AND CATHEPSIN G ISOLATED FROM RAT POLYMORPHONUCLEAR LEUKOCYTES
- ANTI-INFLAMMATORY EFFECT OF A SELECTIVE INHIBITOR OF ELASTASE, CATHEPSIN G AND CHYMOTRYPSIN ON CARRAGEENIN-INDUCED INFLAMMATION IN RATS
- CELLULAR ORIGIN OF CATHEPSIN B IN CARRAGEENIN-INDUCED GRANULOMA TISSUES IN RATS
- PROTEINASE INHIBITORS SUPPRESS THE FORMATION OF GRANULATION TISSUE IN THE CARRAGEENIN-INDUCED INFLAMMATION IN RATS
- A 10-kDa Fragment of Fibronectin Type III Domain Is a Neutrophil Chemoattractant Purified from Conditioned Medium of Rat Granulation Tissue
- Chemokine Receptor CXCR2 Activates Distinct Pathways for Chemotaxis and Calcium Mobilization
- Identification of C3a and N-Truncated C3a as Vascular Permeability-Enhancing Factors from the Exudate of Chronic Phase of Carrageenan-Induced Inflammation in Rats
- INHIBITION BY HYDROXYUREA OF THE REBOUND OF GRANULOMATOUS INFLAMMATION FOLLOWING WITHDRAWAL OF GLUCOCORTICOID THERAPY
- Effects of Cytokine-Induced Neutrophil Chemoattractants (CINCs) on Shape Change, Adhesiveness and Phagocytosis of Rat Neutrophils
- Evidence for Two Putative Receptors Mediating Chemotactic Activity of Cytokine-Induced Neutrophil Chemoattractants (CINCs) for Rat Neutrophils
- EFFECT OF METHYLPREDNISOLONE AND "PULSE" THERAPY WITH METHYLPREDNISOLONE SODIUM SUCCINATE ON AUTOLOGOUS IMMUNE COMPLEX NEPHRITIS IN RATS
- Anti-inflammatory action of progesterone on carrageenin-induced inflammation in rats.
- A new simple plastic chemotaxis device of the Boyden chamber type utilizing an immunoassay plate.