Effect of Propranolol on Blood Pressure and Plasma Renin Concentration in Renovascular Hypertensive Rats
スポンサーリンク
概要
- 論文の詳細を見る
The effect of chronic oral administration of propranolol (39-80mg/Kg/day, for 21-27 days) on blood pressure, plasma renin concentration, and heart rate were studied in 2 types of renovascular hypertensive rats; one-kidney type with normal plasma renin and two-kidney type with high plasma renin. No significant change was observed in the blood pressure of either model during the administration of propranolol in spite of a significant reduction of heart rate. Plasma renin concentration showed a trend of suppression in two-kidney type rats, but this change was not significant. There was no suppression in one-kidney type rats. These results suggest that the beta-adrenergic system may not play a major role either in regulating plasma renin level or in maintaining the blood pressure in renovascular hypertensive rats.
- International Heart Journal刊行会の論文
著者
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Ogino Koichi
Third Division Department Of Internal Medicine
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Pak Chun
Third Division Department Of Internal Medicine Faculty Of Medicine
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Matsunaga Masato
Third Division Department Of Internal Medicine Faculty Of Medicine And College Of Medical Technology
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Yamamoto Jin
Third Division Department Of Internal Medicine
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Kawai Chuichi
Third Department Of Internal Medicine Kyoto University Faculty Of Medicine
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KIRA Jun
Third Department of Internal Medicine, Faculty of Medicine, Kyoto University
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Ogino Koichi
Third Department Of Internal Medicine Faculty Of Medicine Kyoto University
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PAK Chun
Third Department of Internal Medicine, Faculty of Medicine, Kyoto University
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YAMAMOTO Jin
Third Department of Internal Medicine, Faculty of Medicine, Kyoto University
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KIRA Jun
Third Division, Department of Internal Medicine, Faculty of Medicine, Kyoto University
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MATSUNAGA Masato
Third Division, Department of Internal Medicine, Faculty of Medicine, Kyoto University
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MATSUNAGA Masato
Third Department of Internal Medicine, Faculty of Medicine, Kyoto University
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