Acid Angiotensinase, Renin, and Acid Adenosine Triphosphatase in Rat Kidney Lysosomes

スポンサーリンク

概要

• 論文の詳細を見る

• 1. Kidney angiotensinases are located in two kinds of subcellular fraction-lysosomal and microsomal. Lysosomal angiotensinase is active at an acid pH and inhibited by DFP, suggesting a relationship to plasma acid angiotensinase. Most of the activity was released from the particles by freezing and thawing. The microsomal enzyme is active near neutral pH, activated by calcium ion and inhibited by EDTA . 2. About 70 per cent of renin activity was released from the subcellular particles in lysosomal fraction of rat kidney by freeze-thaw method. It revealed only one peak on either Sephadex G-100 gel filtration or DEAE-cellulose column chromatography. The molecular weight of renin was calculated as 40,000-50,000. 3. At least three components of acid ATPase were found in lysosomal fraction of rat kidney by DEAE-cellulose column chromatography.

• 社団法人日本循環器学会の論文
• 1968-03-20

著者

• Takayasu Masao

  Cardiovascular(CV) Reseach and Training Center of Alabama Univ. School of Med.

• Takayasu Masao

  The 3rd Dept. of Med. Clinic., Kyoto Univ. Hosp.

• Kira Jun

  The 3rd Division Department Of Internal Medicine Faculty Of Medicine Kyoto University

• SAITO NOBORU

  Clinical Nutrition Laboratory, Kyoto University Hospital

• OGINO KOICHI

  Third Division, Department of Internal Medicine

• OGINO KOICHI

  The 3rd Medical Clinic, Kyoto University Hospital, Kyoto

• MATSUNAGA MASATO

  The 3rd Department of lnternal Medicine, Faculty of Medicine, Kyoto University

• MATSUNAGA Masato

  Kyoto Univ.

• Ogino Koichi

  The Department Of Internal Medicine Faculty Of Medicine Kyoto University

• Ogino Koichi

  The 3rd Division Department Of Internal Medicine School Of Medicine Kyoto University

• Takayasu Masao

  Kyoto Medical Association For Prevention Of Cardiovascular Disease Kyoto National Hospital

• Takayasu Masao

  3rd Dept. Of Intern. Med. Kyoto Univ.

• MATSUNAGA MASAO

  The 3rd Division of Internal Medicine, School of Medicine, Kyoto University

• SAITO NOBORU

  The 3rd Division of Internal Medicine, School of Medicine, Kyoto University

• Matsunaga Masato

  Third Division Department Of Internal Medicine Faculty Of Medicine And College Of Medical Technology

• Matsunaga Masato

  The 3rd Division Department Of Internal Medicine Faculty Of Medicine Kyoto University

• Ogino Koichi

  Maekatva Clinic Kyoto University Hospital

• Saito Noboru

  Clinical Nutrition Laboratory Kyoto University Hospital

• Kira Jun

  Department Of Internal Medicine National Himeji Hospital

• Kira Jun

  Dept. Of Intern. Med. National Himeji Hosp.

• Kira Jun

  3rd Div. Dept. Of Intern. Med. (prof. M. Maekawa) Facul. Of Med. Kyoto University Kyoto

• Takayasu Masao

  3rd Div. Dept. Of Intern. Med. Kyoto Univ. Hosp.

• Ogino Koichi

  3rd Div. Dept. Of Intern. Med. School Of Med. Kyoto Univ.

• Matsunaga Masato

  Central Clinical Laboratories Kyoto Univ. Hosp.

• Saito Noboru

  3rd Div. Dept. Of Intern. Med. Kyoto Univ. Hosp.

関連論文

• LIGHT MICROSCOPIC STUDY WITH MEASUREMENT OF DIAMETER OF BIOPSIED HUMAN CARDIAC VENTRICULAR MUSCLES WITH HYPERTROPHY, USING 1μ SECTIONS OF PLASTIC BLOCKS STAINED WITH TOLUIDINE BLUE
• THE FIRST DERIVATIVE OF THE APEX CARDIOGRAM AND LEFT VENTRICULAR FUNCTION : PROCEEDINGS OF THE 37TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• EVALUATION OF THE LEFT VENTRICULAR PERFORMANCE IN MITRAL STENOSIS BY SYSTOLIC TIME INTERVALS
• PREVENTION OF NEPHROSCLEROSIS AND CARDIAC HYPERTROPHY BY CAPTOPRIL TREATMENT OF SPONTANEOUSLY HYPERTENSIVE RATS
• HIGH LEVEL OF PLASMA INACTIVE RENIN IN BARTTER'S SYNDROME
• STUDIES ON THE MOLECULAR WEIGHT OF ACTIVE AND INACTIVE RENINS IN ESSENTIAL HYPERTENSION
• Reversibility of Acid-Activation and Cryoactivation of Inactive Renin in Human Plasma : THE 10th CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
• PATHOPHYSIOLOGICAL STUDIES ON HYPERTENSION INDUCED IN RATS BU KIDNEY EXTRACT AND SALT
• Cryoactivation of Inactive Renin in Human Plasma : VIII CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
• MECHANISM OF HYPERTENSION INDUCED IN RATS BY KIDNEY EXTRACT AND 1% SALINE LOADING : IInd Auditorium
• Decreased Early Diastolic dV/dt in Ischemic Heart Disease Observed by ECG-gated Radiocardiography : SYMPOSIUM ON EVALUATION OF CARDIAC FUNCTIONS THROUGH NON-INVASIVE TECHNIQUES
• Plasma Renin and the Antihypertensive Effect of Angiotensin-II Antagonist in Experimental Hypertension
• Plasma Renin and Vascula Complications in Substrains of the Spontaneously Hypertensive Rat, with a Reference to Water and Electrolyte Balance
• PLASMA RENIN AND HYPERTENSIVE VASCULAR COMPLICATIONS : AN OBSERVATION IN THE STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RAT
• Renal Functions in Hypertensive Subjects Evaluated by Computer-aided Radioisotope Renogram : Prognosis and Treatment of Renal Hypertension
• Hypertensive Vascular Lesions and Renin or Lysosomal Enzymes in Rats
• HEMODYNAMIC EFFECTS OF BETA-ADRENERGIC BLOCKADE IN HYPERTENSION : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• CLINICAL STUDIES ON "WATER-ELECTROLYTE REGULATION MECHANISM" IN CHRONIC CONGESTIVE HEART FAILURE
• Clinical Studies on "Water-Electrolyte Regulation Mechanism" in Chronic Congestive Heart Failure : Part III
• The Clinical and Physiological Study relating to the Treatments of Chronic Renal Failure. (I)
• 148. Clinical Studies on the "Water-Electrolyte Regulation Mechanism" in Chronic Congestive Heart Failure
• Obstructive Aortitis with Hypertension : Takayasu's Disease without the Eye Symptoms
• Clinical Study on the Metabolism of Catecholamines in Cardiovascular Diseases (I) Study on the Urinary Excretion of Adrenaline, Noradrenaline and Vanillyl Mandelic Acid ln Hypertension
• THE METABOLIC AND HEMODYNAMIC EFFECTS OF BETA BLOCKERS DURING EXERCISE IN NORMAL ADULTS : Sympathetic Function : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• 90) On the ATP-dephosphorylating Activity in Human Sera
• STUDIES ON MITRAL STENOSIS BY RADIOCARDIOGRAPHY : CHANGE OF BLOOD VOLUME DISTRIBUTION AND ITS EVALUATION BY CARDIAC CATHETERIZATION
• STUDIES ON THE HEMODYNAMIC RESPONSE TO EXERCISE BY RADIOCARDIOGRAPHY : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• QUANTITATIVE ESTIMATION OF AORTIC REGURGITATION BY ANALOG COMPUTER ANALYSIS OF RADIOCARDIOGRAM
• DETERMINATION OF INTRACARDIAC SHUNTS IN PATIENTS WITH CONGENITAL HEART DISEASE BY MEANS OF ANALOG SIMULATION OF RADIOCARDIOGRAM
• STUDY ON CARDIO CEREBRAL HEMODYNAMICS IN POSTURAL CHANGES (I)
• DETERMINATION OF AORTIC REGURGITATION RATE BY ANALOG SIMULATION OF RADIOCARDIOGRAM : PROCEEDINGS OF THE 35TH ANNUAL MEETlNG OF THE JAPANESE CIRCULATION SOCIETY (Part III)
• STUDIES ON SERUM ENZYMES - SPECIALLY LDH-ISOENZYMES -IN CASES SHOWN BY ECG OF "SO-CALLED" VARIANT FORM OF ANGINA PECTORIS : PROCEEDINGS OF THE 35TH ANNUAL MEETlNG OF THE JAPANESE CIRCULATION SOCIETY (Part III)
• CLINICAL STUDY ON CEREBRAL HEMODYNAMICS FROM ANALOG COMPUTER ANALYSIS OF CEREBRO-ENCEPHALOGRAM
• ESTIMATION OF HEART VOLUME BY ANALOG SIMULATION OF RADIOCARDIOGRAM
• 119. Clinical Study on the Metabolism of Catecholamines in Cardiovascular Diseases II : Study on the Urinary Excretion of Adrenaline, Noradrenaline and Vanillyl Mandelic Acid in Congestive Heart Failure
• HISTOLOGICAL FlNDINGS IN RATS MADE HYPERTENSIVE BY INJECTION OF RENAL EXTRACTS : REINVESTIGATION OF RENAL PRESSOR SUBSTANCE. REPORT NO. 5 : Proceedlngs of the 35th Annual Meetlng of the Japanese Circulation Society (part I)
• THE EFFECT OF L-TYROSINE ON THE BLOOD PRESSURE AT ACUTE STAGE IN EXPERIMENTAL HYPERTENSION : (Part II)
• ANALYSIS OF HYPERTENSION-INDUCING SUBSTANCE BY GEL FILTRATION METHOD : REINVESTIGATION OF RENAL PRESSOR SUBSTANCE NO. 11
• PRELIMINARY COMMUNICATION ON THE DISCREPANCY BETWEEN RENIN ACTIVITY AND HYPERTENSION-INDUCING POTENCY IN RAT KIDNEY EXTRACT DUAL RENAL PRESSOR SUBSTANCE HYPOTHESIS
• HIGH BLOOD PRESSURE FOLLOWING INJECTION OF RENAL EXTRACTS FROM RATS UNDER VARIOUS EXPERIMENTAL CONDITIONS AND A YPOTHESIS : DUAL RENAL PRESSOR SUBSTANCE THEORY (REINVESTIGATION OF RENAL PRESSOR SUBSTANCE, REPORT N0.1) : Proceedings of the 34th Annual Meet
• STUDIES ON IDENTITY OF HEMOCONCENTRATING SUBSTANCE (HCS) WITH RENIN
• ELECTRON MICROSCOPIC CYTOCHEMISTRY OF THE HEART II ACID PHOSPHATASE ACTIVITY WITH SPECIAL REFERENCE TO THE LYSOSOMAL ACTIVITIES IN THE WORKING MYOCARDIUM : (Part III)
• STUDIES ON THE CARDIAC FUNCTION IN THE FAILING HEART EXPERIMENTAL AORTIC INSUFFICIENCY
• Distenssbility Characteristics of the Pulmonary "Venous" System estimated by the Right Heart Catheterization in Normal and Abnormal Heart (A Preliminary Report) : PROCEEDINGS OF THE 23RD KINKI REGIONAL MEETING
• The Effect of Furosemide on the Hemodynamics of the Heart : Part III
• Studies on Cardiopulmonary Circulatory Dynamics in Various Heart Diseases by means of ^I MAA
• 10) Changee in Total Blood Volume Utilizing I^131Labeled Albumin in Chronic Congestive Heart Failure
• Clinical Studay on the Treatment of Sclerotic Coronary Insufficiency : (I) Influence of Combined Administration of Prednisolone and Chlorothiazide
• A NEW INDEX FOR LEFT VENTRICULAR CONTRACTILITY dP/dt/(P/t) : (Part II)
• ANALYSIS OF VENTRICULAR SEPTAL MOTION IN ASD : PROCEEDINGS OF THE 37TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• AN ATTEMPT TO VOLUME ESTIMATION OF THE RIGHT VENTRICLE BY ANGIOGRAPHY : PROCEEDINGS OF THE 37TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• THE STUDY OF LEFT VENTRICULAR PERFORMANCE IN DIASTOLE BY UCG
• HISTOCHEMICAL DEMONSTRATION OF ATPase ACTIVITY IN PERIPHERAL NERVE FIBERS OF RAT
• ANGIOCARDIOGRAPHIC STUDY OF LEFT VENTRICLE AND VECTORCARDIOGRAM
• Detection of Circulatory Shunts by Means of External Counting Method Differentiation between ASD and VSD, Semiquantitative Estimation of Left-to-Right Shunt, and the Detection of Right-to-Left Shunt
• 32. A Study on the Conduction Pathways of the Excitation in Rabbit's Right Atrium under High Potassium Tyrode Perfusion, by means of Multiple Micro-suction Electrodes
• COLUMN CHROMATOGRAPHIC ANALYSIS OF RELATOINSHIP BETWEEN HYPERTENSION-INDUCING POTENCY AND RENIN CONTENT OF KIDNEY EXTRACT
• Analysis of Relationship Between Renin-Angiotensin System and Blood Pressure in Experimental Hypertension Induced by Kidney Extract (3 Conference of Pathogenesis of Hypertension)
• Lysosomal Enzyme Activities in Rat Kidney treated with DOCA, especially with Reference to Renin, Cathepsin and β-Glucuronidase
• RENAL VASCULAR LESIONS AND RENIN ACTIVITIES IN RATS TREATED WITH DOCA PLUS HIGH SALT OR WITH HIGH SALT : (Part III)
• ADRENALECTOMY AND KIDNEY RENIN : (Part III)
• -98-ENERGY UTILIZATION OF HYPERTROPHIED SHR AND SHR-SP HEART : Ventricular Function : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• PRODUCTION AND RELEASE OF ACTIVE AND INACTIVE FORMS OF RENIN BY CULTURED HUMAN VASCULAR SMOOTH MUSCLE CELLS : Hypertension (I) : FREE COMMUNICATIONS (I) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• THE SPONTANEOUSLY HYPERTENSIVE RAT AND RENAL PRESSOR SUBSTANCE : REINVESTIGATION OF RENAL PRESSOR SUBSTANCE, REPORT NO. 10
• STUDY ON THE RELEASE OF RAT KIDNEY LYSOSOMAL ENZYMES
• Acid Angiotensinase as a Lysosomal Enzyme
• 76. Studies on the Role of Lysosomes in the Pathogen-e-sis of Cardiovascular Diseases. IV. Acid Angiotensinase Activity in Lysosomes of Rat Tissues
• 75. Study on Mucopolysaccharase Activity in Lysosome of Rat-Kidney
• Amino Acid Analysis after Degradation of Angiotensin II by Rat Kidney Lysosomes
• Acid Angiotensinase, Renin, and Acid Adenosine Triphosphatase in Rat Kidney Lysosomes
• Hemoconcentrating Substance and Vascular Permeability Factor from Rat Kidney Lysosomes : Possible Involvement of Lysosomes in the Pathogenesis of Cardiovascular Diseases
• Studies on the Role of Lysosomes in the Pathogenesis of Cardiovascular Diseases Report No. 1 : Renin, Acid ATPase and Vascular Permeability Factor in Rat Kidney Subcellular Particles : Part II
• The Study of Human Serum ATPase (II)
• STUDY ON A ROLE OF LYSOSOMAL ENZYMES IN PATHOGENSSIS OF CARDIOVASCULAR DISEASES (VII) : Hypertension and the Release of Rat Kidney Lysosomal Enzymes : Proceedings of the 34th Annual Meeting of the Japanese Circulation Society (Part II)
• Renin and Acid Adenosine Triphosphatase as Lysosomal Enzymes
• 80) The Study of Acid ATPase in Human Sera
• 66) On the Kidney ATPase ; Sodium and Potassium activated Adenosine Triphosphatase in a Rat Kidney
• Studies on the Structure and Function of the Kidney (II) : Correlation between Histological Findings and Clinical Pictures in Essential Hypertension and the Aged
• Occlusive Thromboaortopathy : Its Clinical Features, Treatment, Follow-up Study and Some Biospy Findings of the Deep Femoral Arteries : Part III
• Lung Scan of the Patients with Occulusive Thromboaortopathy (So-called Takayasu's Disease)
• Clinical Study on Lipid Metabolism Effect of Glucose and Insulin on Nefa Metabolism
• Some Studies on Gamma Globulin in the Human Arterial Wall Preliminary Report
• Cardiovascular Reflex on Essential Hypertension : I. Carotid Sinus Block and Norepinephrine Test
• Studies on the Serum ATPase in Cardiovascular and Renal Diseases
• Study of Electrolyte Metabolism in Circulatory Disorders : 1. Effects of Low Sodium Diet on Electrolyte Metabolism in Hypertensive Patients
• 88) Blood Pressure Response of the Fractions Extracted from Arterial and Venous Sera of Dogs.
• 87) The Effect of Serum Fractions from the Normotensive on the Blood Pressure of Dog.
• 86) Pressor Substance in the Serum of the Hypertensive, Related to "ATP-ase Maekawa"
• 83) ATP-dephosphorylating Activity of the Serum Fractions Extracted from the Hypertensive and Dog Arterial and Venous Blood.
• 109) Blood ATP Level in Patients of Various Diseases, Especially of Cardiovascular Diseases(Proceedings of the 18th Annual Meeting of the Japanese Circulation Society)
• 107) Further Studies on the Enzymatic and Physiological Properties of Kidney-ATP-ase(Proceedings of the 18th Annual Meeting of the Japanese Circulation Society)
• 106) On the Dephosphorylation of Adenosinetriphosphate by Human Sera and Urines(Proceedings of the 18th Annual Meeting of the Japanese Circulation Society)
• CONTINUOUS ELECTROCARDIOGRAPHIC RECORDINGS AND SERIAL CHANGES OF VARIOUS SERUM ENZYMES IN A PATIENT WITH VARIANT FORM OF ANGINA PECTORIS
• Clinical Observation of Heart Tumors
• Hypertension-Inducing Potency and Renin Content of Variously Treated Kidney Extract
• Renal Function, Plasma Renin, and Spontaneous Diuresis in an Advanced Stage of Hypertension in Rats
• Effects of Beta-Adrenergic Blocking Agents on the Blood Pressure, Plasma Renin Activity and Hemodynamics of Hypertensive Patients
• 178) The Effect of Glucose and Insulin on Nefa Metabolism
• Serum Cholesterol of Normal Human Subjects in Kyoto Area
• Studies on Kidney ATPase (2)

もっと見る 閉じる

スポンサーリンク