Effects of Beta-Adrenergic Blocking Agents on the Blood Pressure, Plasma Renin Activity and Hemodynamics of Hypertensive Patients

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概要

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• Changes in blood pressure, plasma renin activity, and hemodynamic components were studied in 23 patients with essential hypertension treated with oral pindolol or propranolol. These beta-adrenergic blocking agents effectively lowered the blood pressure in the majority of the patients. Although plasma renin activity was not significantly changed, the higher was the pretreatment level, the more it tended to be decreased. Systemic vascular resistance was significantly decreased, while changes in cardiac index and circulating blood volume were variable. Pindolol showed less effect in reducing the heart rate than propranolol. The antihypertensive effect of these drugs had no correlation with the change in plasma renin activity or in any one of hemodynamic components.

• International Heart Journal刊行会の論文

著者

• HARA AKIRA

  Third Department of Medicine, Kyoto University, School of Medicine

• PAK CHUN

  Third Division, Department of Internal Medicine, Faculty of Medicine

• YAMAMOTO JIN

  Third Division, Department of Internal Medicine

• MATSUNAGA MASATO

  Third Division, Department of Internal Medicine

• OGINO KOICHI

  Third Division, Department of Internal Medicine

• MATSUNAGA Masato

  Kyoto Univ.

• MOTOHARA Seiichiro

  Third Department of Internal Medicine, Faculty of Medicine, Kyoto University

• SAITO Muneyasu

  Third Department of Internal Medicine, Faculty of Medicine, Kyoto University

• Ogino Koichi

  Third Division Department Of Internal Medicine

• Pak Chun

  Third Division Department Of Internal Medicine Faculty Of Medicine

• Matsunaga Masato

  Third Division Department Of Internal Medicine Faculty Of Medicine And College Of Medical Technology

• Matsunaga Masato

  The 3rd Division Department Of Internal Medicine Faculty Of Medicine Kyoto University

• Yamamoto Jin

  Third Division Department Of Internal Medicine

• Hara Akira

  Third Department Of Medicine Kyoto University School Of Medicine

• Matsunaga Masato

  Central Clinical Laboratories Kyoto Univ. Hosp.

• Ogino Koichi

  Third Department Of Internal Medicine Faculty Of Medicine Kyoto University

• PAK Chun

  Third Department of Internal Medicine, Faculty of Medicine, Kyoto University

• YAMAMOTO Jin

  Third Department of Internal Medicine, Faculty of Medicine, Kyoto University

• MATSUNAGA Masato

  Third Department of Internal Medicine, Faculty of Medicine, Kyoto University

• HARA Akira

  Third Department of Internal Medicine, Faculty of Medicine, Kyoto University

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