PLASMA RENIN AND HYPERTENSIVE VASCULAR COMPLICATIONS : AN OBSERVATION IN THE STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RAT
スポンサーリンク
概要
- 論文の詳細を見る
The hypothesis that plasma renin is a major risk factor in the development of cardiovascular complications of hypertension was evaluated in a model animal, the spontaneously hypertensive rat (SHR). Plasma renin levels and pathological findings were studied in stroke-prone and -resistant strains of SHR at various ages. The stroke-prone strain showed significantly higher plasma renin levels at and after seven months of age, while the stroke-resistant strain showed no significant differences from the control at any age. High plasma renin levels were always associated with evident vascular complications in the kidney and the brain, indicating underlying angionecrosis and malignant transformation of hypertension. However, no evidence indicated that a higher plasma renin preceded the development of vascular lesions. Thus the high plasma renin would be a result rather than the cause of hypertensive vascular lesions.
- 社団法人日本循環器学会の論文
- 1976-01-20
著者
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Hara Akira
First Department Of Internal Medicine. Fukui Medical School
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Yamori Yukio
Department Of Pathology Faculty Of Medicine Kyoto University
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OKAMOTO KOZO
Department of Palhology, Faculty of Medicine, Kyoto University
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Hara A
First Department Of Internal Medicine. Fukui Medical School
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OGINO KOICHI
Third Division, Department of Internal Medicine
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HARA AKIRA
The 3rd Medical Clinic, Kyoto University Hospital, Kyoto
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OGINO KOICHI
The 3rd Medical Clinic, Kyoto University Hospital, Kyoto
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YAMAMOTO JIN
The 3rd Division, Department of lnternal Medicine, Faculty of Medicine, Kyoto University
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MATSUNAGA MASATO
The 3rd Department of lnternal Medicine, Faculty of Medicine, Kyoto University
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MATSUNAGA Masato
Kyoto Univ.
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Hirakawa Akina
From The Third Division Department Of Internal Medicine Kyoto University
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Hara A
Department Of Applied Biological Chemistry Faculty Of Agriculture Meijo University
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Yamamoto Jin
National Cardiovascular Center Researchinstitute
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Yamamoto Jjn
Dept. Of Intern. Med. National Himeji Hosp.
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Yamamoto Jin
The 3rd Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Ogino Koichi
The Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Ogino Koichi
The 3rd Division Department Of Internal Medicine School Of Medicine Kyoto University
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Okamoto Kozo
Department Of Pathology Faculty Of Medicine Kyoto University
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Yamamoto Jin
National Himeji Hosp. Dept. Of Intern. Med
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Ogino Koichi
Third Division Department Of Internal Medicine
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Ogino Koichi
3rd Dept. Of Intern. Med. Kyoto Univ.
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Hirakawa Akiha
3rd Dept. Of Intern. Med. Kyoto Univ.
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Ogino Koichi
3rd Division Dept. Of Intern. Med. Kyoto Univ. Sch. Of Med.
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Matsunaga Masato
Third Division Department Of Internal Medicine Faculty Of Medicine And College Of Medical Technology
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Hara Akira
From The Third Division Department Of Internal Medicine Kyoto University
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Yamori Yukio
Dept. Of Pathology Kyoto Univ. School Of Med.
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Matsunaga Masato
The 3rd Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Yamamoto Jin
Third Division Department Of Internal Medicine
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Ogino Koichi
Maekatva Clinic Kyoto University Hospital
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Okamoto Kozo
Department Of Palhology Faculty Of Medicine Kyoto University
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Hirakawa Akina
3rd Medical Clinic Faculty Of Medicine Kyoto University
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Ogino Koichi
3rd Div. Dept. Of Intern. Med. School Of Med. Kyoto Univ.
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Hara Akira
The 3rd Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Matsunaga Masato
Central Clinical Laboratories Kyoto Univ. Hosp.
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Yamori Yukio
Department of Pathology, Faculty of Medicine, Kyoto University
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Yamori Yukio
Department of Life Science, Graduate School of Human and Environmental, Kyoto University
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Okamoto Kozo
Department of Clinical Functional Physiology, Toho University
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