Studies on the Biosynthesis of Fosfomycin. Conversion of 2-Hydroxyethylphosphonic Acid and 2-Aminoethylphosphonic Acid to Fosfomycin
スポンサーリンク
概要
著者
-
SATOH ATSUYUKI
Pharmaceutical Technology Laboratories, Meiji Seika Kaisha Ltd.,
-
Otake Noboru
Institute Of Applied Microbiology The University Of Tokyo
-
Seto Haruo
Institute Of Applied Microbiology The University Of Tokyo
-
Ogawa Hiroshi
Pharmaceutical Development Laboratories Meiji Seika Kaisha Ltd.
-
IMAI Satoshi
Pharmaceutical Development Laboratories, Meiji Seiko Kaisha Ltd.
関連論文
- Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neurons from Excitotoxicity : II. Structure Determination
- Structure of Aspochalasin H, a New Member of the Aspochalasin Family
- Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neuronal Cells from Excitotoxicity : I. Fermentation, Isolation, Physico-chemical Properties and Biological Activity
- Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. : II. Physico-chemical Properties and Structure Elucidation
- Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. : I. Production, Isolation and Biological Activity
- Selective Cytotoxicity and Stereochemistry of Aspochalasin D
- Phoenistatin, A New Gene Expression-Enhancing Substance Produced by Acremonium fusigerum
- Rustmicin, a New Macrolide Antibiotic Active Against Wheat Stem Rust Fungus(Organic Chemistry)
- Isolation and Structural Determination of a New Antibiotic Curromycin B
- Spicamycin, a New Differentiation Inducer of Mouse Myeloid Leukemia Cells (Ml) and Human Promyelocytic Leukemia Cells (HL-60)
- Propanosine (K-76), a New Antibiotic Active against Valsa ceratosperma, the Pathogen of Apple Canker Disease
- Taxonomy of Producing Organism, and Production, Isolation, Physico-chemical Properties and Biological Activities of Cirratiomycin A and B
- Phenazostatin C, a New Diphenazine with Neuronal Cell Protecting Activity from Streptomyces sp.
- New Diphenazines with Neuronal Cell Protecting Activity, Phenazostatins A and B, Produced by Streptomyces sp.
- Bacillus subtilis ypgA Gene Is fni, a Nonessential Gene Encoding Type 2 Isopentenyl Diphosphate Isomerase
- Diheteropeptin, a Novel Substance with TGF-β-like Activity, Produced by a Fungus, Diheterospora chlamydosporia : II. Physico-chemical Properties and Structure Elucidation
- Diheteropeptin, a New Substance with TGF-β-like Activity, Produced by a Fungus, Diheterospora chlamydosporia : I. Production, Isolation and Biological Activities
- Structure of a New Anthracycline, Cinerubin Y, Produced by a Blocked Mutant of Streptomyces violaceochromogenes Transformed by pIJ702(Organic Chemistry)
- A New Depsipeptide Antibiotic, Citropeptin(Microbiology & Fermentation Industry)
- A New Depsipeptide Antibiotic, Variapeptin(Microbiology & Fermentation Industry)
- Rasfonin, a New Apoptosis Inducer in ras-dependent Cells from Talaromyces sp.
- Cytovaricin B, a New Inhibitor of JAK-STAT Signal Transduction Produced by Streptomyces torulosus
- Screening of Microbial Products Modifying the Action of Lepin (Obese Gene Product by a Biosensor)
- Microbial and Chemical Conversion of Antibiotic K-41. I. Isolation and Identification of Conversion Product
- Nucleotide Sequences of Genes Encoding Allosamidin-sensitive and -insensitive Chitinases Produced by Allosamidin-producing Streptomyces(Biochemistry & Molecular Biology)
- A New Screening Method for C-P Compound Producing Organisms by the Use of Phosphoenolpyruvate Phosphomutase(Biological Chemistry)
- Cloning and Expression in Escherichia coli of 2-Hydroxypropylphosphonic Acid Epoxidase from the Fosfomycin-producing Organism, Pseudomonas syringae PB-5123
- Nucleotide Sequence of Fortimicin KL1 Methyltransferase Gene Isolated from Micromonospora olivasterospora, and Comparison of Its Deduced Amino Acid Sequence with Those of Methyltransferases Involved in the Biosynthesis of Bialaphos and Fosfomycin
- Absolute Configuration of Spicamycin, an Antitumor Antibiotic Produced by Streptomyces alanosinicus
- Structures of New Saponins Isolated from Bupleurum kunmingense Y. Li et S. L. Pan(Organic Chemistry)
- Isolation of Triterpenoid Glycosides (Saikosaponins) from Bupleurum polyclonum Y. Li et S. L. Pan and Their Chemical Structures(Organic Chemistry)
- Stachybocins, Novel Endothelin Receptor Antagonists, Produced by Stachybotrys sp.M6222 II.Structure Determination of Stachybocins A, Band C
- Isolation and Structure of Isobutyrylleucanicidin Produced by Streptomyces halstedii
- The Structure of Leucanicidin, a Novel Insecticidal Macrolide Produced by Streptomyces halstedii
- Trichostatin D, a New Inducer of Phenotypic Reversion in Transformed Cells
- Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus
- Detection of the Mevalonate Pathway in Streptomyces Species by Utilization of the 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene
- Scale-up of Bialaphos Production
- Effect of Oxygen Partial Pressure on Bialaphos Synthesis, Sugar Metabolism and the Activity of Tricarboxylic Acid Cycle Enzymes in Submerged Culture of Streptomyces hygroscopicus : Studies on Production of Bialaphos (III).
- Accumulation of Bialaphos Intermediates under High Oxygen Partial Pressure and Their Conversion to Bialaphos : Studies on the Production of Bialaphos(IV).
- Purification and Characterization of Poly(γ-glutamic acid) Hydrolase from a Filamentous Fungus, Myrothecium sp. TM-4222
- Screening for Microorganisms Having Poly(γ-glutamic acid) Endohydrolase Activity and the Enzyme Production by Myrothecium sp. TM-4222
- Carquinostatin B, a New Neuronal Cell-protecting Substance Produced by Streptomyces exfoliatus
- A Novel Neuronal Cell Protecting Substance, Naphthomycinol, Produced by Streptomyces sp. PF7
- A Novel Neuronal Cell Protecting Substance, Espicufolin, Produced by Streptomyces sp. cu39
- Cinnatriacetins A and B, New Antibacterial Triacetylene Derivatives from the Fruiting Biodies of Fistulina hepatica
- New Ravidomycin Analogues, FE35A and FE35B, Apotosis Inducers Produced by Streptomyces rochei
- A Novel Neuronal Cell Protecting Substance, Aestivophoenin C, Produced by Streptomyces purpeofuscus
- 6-Hydroxytetrangulol, a New CPP32 Protease Inducer Produced by Streptomyces sp.
- A Novel Substance with TGF-β like Activity, Diheteropeptin, Produced by a Fungus, Diheterospora sp.
- Isolation and Structure Elucidation of Novel Neuronal Cell Protecting Substances, Carazomadurins A and B Produced by Actinomadura madurae
- Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D II. Physicochemical Properties and Structure Elucidation
- Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D I. Taxonomy, Fermentation, Isolation and Biological Activities
- Diazaphilonic Acid, a New Azaphilone with Telomerase Inhibitory Activity
- Synthesis of 4'-O-Acylanthracyclines(Organic Chemistry)
- A Neuronal Cell Protecting Substance, 4-Demethoxymicigazone, produced by Streptomyces halstedii
- Breeding of Bialaphos Producing Strains from a Biochemical Engineering Viewpoint : Studies on the Production of Bialaphos (I).
- Apoptolidin, a New Apoptosis Inducer in Transformed Cells from Nocardiopsis sp.
- Novel Neuronal Cell Protecting Substances, Aestivophoenins A and B, Produced by Streptomyces purpeofuscus
- A New Neuronal Cell Protecting Substance, Lavanduquinocin, Produced by Streptomyces viridochromogenes
- Formobactin, a Novel Radical Scavenging and Neuronal Cell Protecting Substance from Nocardia sp
- Thiopeptide Non-producing Streptomyces Species Carry the tipA Gene : A Clue to Its Function
- Comparison of Two C-P Bond-forming Enzymes Involved in the Biosynthesis of Bialaphos(Biological Chemistry)
- Major Anthocyanin of the Flowers of Hibiscus (Hibiscus rosa-sinensis L.)(Organic Chemistry)
- Growth-phase Dependent Expression of the Mevalonate Pathway in a Terpenoid Antibiotic-producing Streptomyces Strain(Microbiology & Fermentation Technology)
- Cloning of a Gene Cluster Encoding Enzymes Responsible for the Mevalonate Pathway from a Terpenoid-antibiotic-producing Streptomyces Strain(Microbiology & Fermentation Technology)
- The Structure of Enacyloxin II, a Novel Linear Polyenic Antibiotic Produced by Gluconobacter sp. W-315(Organic Chemistry)
- Fluorinated Blasticidin S(Organic Chemistry)
- Crystal Structure of 1-Deoxy-D-xylulose 5-phosphate Reductoisomerase Complexed with Cofactors : Implications of a Flexible Loop Movement upon Substrate Binding
- Studies on the Biosynthesis of Terpenoidal Compounds Produced by Actinomycetes 2. Biosynthesis of Carquinostatin B via the Non-mevalonate pathway in Streptomyces exfoliatus
- Construction and Characterization of Escherichia coli Disruptants Defective in the yaeM Gene
- Structure of a New Antioxidative Phenolic Diterpene Isolated from Rosemary (Rosmarinus officinalis L.)
- Anguinomycins C and D, New Antitumor Antibiotics with Selective Cytotoxicity against Transformed Cells
- Biosynthesis of a Natural C-P Compound, Bialaphos Produced by Streptomyces hygroscopicus
- Studies on the Biosynthesis of Bialaphos. Biochemical Mechanism of C-P Bond Formation: Discovery of Phosphonopyruvate Decarboxylase which Catalyzes the Formation of Phosphonoacetaldehyde from Phosphonopyruvate
- Biochemical Mechanism of C-P Bond Formation of Bialaphos : Use of Gene Manipulation for the Analysis of the C-P Bond Formation Step(Biological Chemistry)
- Studies on the Biosynthesis of Bialaphos (SF-1293). 18. 2-Phosphinomethylmalic Acid Synthase: A Descendant of (R)-Citrate Synthase?
- Turmeronol A and Turmeronol B, New Inhibitors of Soybean Lipoxygenase(Organic Chemistry)
- Production of Poly(γ-glutamic acid) by Bacillus subtilis F-2-01
- Purification and Characterization of Citrate Synthase from Streptomyces hygroscopicus SF-1293 and Comparison of Its Properties with Those of 2-Phosphinomethylmalic Acid Synthase(Biological Chemistry)
- Promoinducin, a Novel Thiopeptide Produced by Streptomyces sp. SF2741
- Trachyspic Acid, a New Metabolite Produced by Talaromyces trachyspermus, that Inhibits Tumor Cell Heparanase:Taxonomy of the Producing Strain, Fermentation, Isolation, Structural Elucidation, and Biological Activity
- Isolation and Structural Elucidation of Antioxidative Substances, Carbazoquinocins A to F
- Selective Cytotoxicity of Mycophenolic Acid against Transformed Cells
- Assignments of the ^1H- and ^C-NMR Spectra of Four Lycopodium Triterpenoids by the Application of a New Two-dimensional Technique, Heteronuclear Multiple Bond Connectivity (HMBC)(Organic Chemistry)
- The Structures of Cirratiomycin A and B, the New Peptide Antibiotics
- The Structures of Myocotrienins I. and II, a Novel Class of Ansamycin Antibiotic
- Isolation and Structures of New Peptide Antibiotics, Cirratiomycin A and B
- The Structures of Diethylaminoethylated Glucose and Oligosaccharides Derived from Cationic Starch
- The Structure of Latosillan, a New Differentiation Inducer of Mouse Myeloid Leukemia Cells (M 1)
- Capoamycin, a New Isotetracenone Antibiotic
- Studies on the Biosynthesis of Fosfomycin. Conversion of 2-Hydroxyethylphosphonic Acid and 2-Aminoethylphosphonic Acid to Fosfomycin
- Anti-conidial Germination Factors Induced in the Presence of Probenazole in Infected Host Leaves. III. Structural Elucidation of Substances A and C
- Studies on Apple Canker Disease. The Necrotic Toxins Produced by Valsa ceratosperma
- Latosillan, a New Differentiation Inducer of Mouse Myeloid Leukemia Cells (Ml): Taxonomy, Fermentation, Isolation, Physicochemical Properties and Biological Properties
- Isolation of New Saponins from the Aerial Part of Bupleurum kunmingense Y. Li et S. L. Pan
- Kerriamycins A, B and C, New Isotetracenone Antibiotics
- Isolation of Triterpenoid Glycosides (Saikosaponins) from Bupleurum kunmingense and Their Chemical Structures
- A New Triterpenoid Glycoside from Bupleurum chinense DC
- The Structures of Minor Congeners of the Detoxin Complex