Absolute Configuration of Spicamycin, an Antitumor Antibiotic Produced by Streptomyces alanosinicus

スポンサーリンク

概要

• 論文の詳細を見る
• 1995-08-25

著者

• HAYAKAWA YOICHI

  Institute of Molecular and Cellular Biosciences, The University of Tokyo

• SETO Haruo

  Institute of Molecular and Cellular Biosciences, The University of Tokyo

• Shimazu A

  Osaka City Univ. Medical School Osaka Jpn

• Shimazu A

  Institute Of Applied Microbiology The University Of Tokyo

• SHINDO Kazutoshi

  Pharmaceutical Research Laboratory, Kirin Brewery Co. Ltd.

• KOBAYASHI Kimiko

  The Institute of Physical and Chemical Research

• OTAKE Noboru

  Department of Biosciences, School of Science and Engineering, Teikyo University

• Kawai Hiroyuki

  Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.

• SAKAI Teruyuki

  Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.

• ODAGAWA Atsuo

  Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.

• SUZUKI Akashi

  Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.

• Hayakawa Yoichi

  Institute Of Low Temperature Science Hokkaidou University

• Shindo Kazutoshi

  Pharmaceutical Research Laboratories Kirin Brewery Co. Ltd.

• Kawai Hiroyuki

  Pharmaceutical Laboratory Kirin Brewery Co. Ltd.

• Kawai H

  Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.

• Kawai H

  Kirin Brewery Co. Ltd.

• Otake N

  Department Of Biosciences Teikyo University

• Suzuki Akashi

  Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.

• Odagawa Atsuo

  Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.

• Sakai Teruyuki

  Pharmaceutical Research Laboratory

• Hayakawa Y

  Faculty Of Pharmaceutical Sciences Tokyo University Of Science

• Seto Haruo

  Institute Of Molecular And Cellular Biosciences The University Of Tokyo

• Otake Noboru

  Department Of Biosciences Teikyo University

• Shindo K

  Japan Women's Univ. Tokyo Jpn

• Hayakawa Yoichi

  Institute Of Applied Microbiology The University Of Tokyo

• Seto Haruo

  Institute Of Applied Microbiology The University Of Tokyo

• Hayakawa Yoichi

  Institute Of Molecular And Cellular Biosciences University Of Tokyo

• Kobayashi Kimiko

  The Institute Of Physical And Chemical Research(riken)

関連論文

• Oximidine III, a New Antitumor Antibiotic against Transformed Cells from Pseudomonas sp. II. Structure Elucidation
• Oximidine III, a New Antitumor Antibiotic against Transformed Cells from Pseudomonas sp. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity
• Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neurons from Excitotoxicity : II. Structure Determination
• Synthesis of the Optical Isomers of 4-[1-(4-tert-Butylphenyl)-2-oxo-pyrrolidine-4-yl]methyloxybenzoic Acid (S-2) and Their Biological Evaluation as Antilipidemic Agent
• Isolation and Structure Elucidation of Vicenistatin M, and Importance of the Vicenisamine Aminosugar for Exerting Cytotoxicity of Vicenistatin
• Byssochlamysol, a New Antitumor Steroid against IGF-1-dependent Cells from Byssochlamys nivea II. Physico-chemical Properties and Structure Elucidation
• Byssochlamysol, a New Antitumor Steroid against IGF-1-dependent Cells from Byssochlamys nivea I, taxonomy, Fermentation, Isolation and Biological Activity
• Structure of Aspochalasin H, a New Member of the Aspochalasin Family
• A Novel Neuronal Cell Protecting Substance, Halxazone, Produced by Streptomyces halstedii
• Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neuronal Cells from Excitotoxicity : I. Fermentation, Isolation, Physico-chemical Properties and Biological Activity
• Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. : II. Physico-chemical Properties and Structure Elucidation
• Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. : I. Production, Isolation and Biological Activity
• Selective Cytotoxicity and Stereochemistry of Aspochalasin D
• Phoenistatin, A New Gene Expression-Enhancing Substance Produced by Acremonium fusigerum
• Production and Characterization of Osteoclast-specific Monoclonal Antibodies
• Simple Isolation Technique for Osteoclasts from Medullary Bones
• Study on the Mechanism of the Antirachitic Effects of T_3
• Ameliorating Effects of Thyroid Hormone on Rickets Induced by a New Rachitogenic Diet
• An Approach to a Computer Analysis of Histologic Images of Giant Cell Tumor of Bone and Osteosarcoma
• Immunohistochemical Demonstration of Carbonic Anhydrase in Human Kidney, Bone and Giant Cell Tumor of Bone
• Rustmicin, a New Macrolide Antibiotic Active Against Wheat Stem Rust Fungus(Organic Chemistry)
• Isolation and Structural Determination of a New Antibiotic Curromycin B
• Spicamycin, a New Differentiation Inducer of Mouse Myeloid Leukemia Cells (Ml) and Human Promyelocytic Leukemia Cells (HL-60)
• Propanosine (K-76), a New Antibiotic Active against Valsa ceratosperma, the Pathogen of Apple Canker Disease
• Taxonomy of Producing Organism, and Production, Isolation, Physico-chemical Properties and Biological Activities of Cirratiomycin A and B
• Phenazostatin C, a New Diphenazine with Neuronal Cell Protecting Activity from Streptomyces sp.
• New Diphenazines with Neuronal Cell Protecting Activity, Phenazostatins A and B, Produced by Streptomyces sp.
• Bacillus subtilis ypgA Gene Is fni, a Nonessential Gene Encoding Type 2 Isopentenyl Diphosphate Isomerase
• Diheteropeptin, a Novel Substance with TGF-β-like Activity, Produced by a Fungus, Diheterospora chlamydosporia : II. Physico-chemical Properties and Structure Elucidation
• Diheteropeptin, a New Substance with TGF-β-like Activity, Produced by a Fungus, Diheterospora chlamydosporia : I. Production, Isolation and Biological Activities
• Structures of Oryzalides A and B, and Oryzalic Acid A, a Group of Novel Antimicrobial Diterpenes, Isolated from Healthy Leaves of a Bacterial Leaf Blight-resistant Cultivar of Rice Plant(Organic Chemistry)
• Structure of a New Anthracycline, Cinerubin Y, Produced by a Blocked Mutant of Streptomyces violaceochromogenes Transformed by pIJ702(Organic Chemistry)
• A New Depsipeptide Antibiotic, Citropeptin(Microbiology & Fermentation Industry)
• A New Depsipeptide Antibiotic, Variapeptin(Microbiology & Fermentation Industry)
• Rasfonin, a New Apoptosis Inducer in ras-dependent Cells from Talaromyces sp.
• Cytovaricin B, a New Inhibitor of JAK-STAT Signal Transduction Produced by Streptomyces torulosus
• Screening of Microbial Products Modifying the Action of Lepin (Obese Gene Product by a Biosensor)
• Microbial and Chemical Conversion of Antibiotic K-41. I. Isolation and Identification of Conversion Product
• Oxygenation Reactions of Various Tricyclic Fused Aromatic Compounds Using Escherichia coli and Streptomyces lividans Transformants Carrying Several Arene Dioxygenase Genes(Microbiology & Fermentation Technology)
• Contribution of N-terminal and Loop Regions of GBP to the Interaction with Epidermal Growth Factor Receptor
• FUNCTION OF INSECT CYTOKINE GBP IN EMBRYOGENESIS OF CABBAGE ARMYWORM, MAMESTRA BRASSICAE(Biochemistry,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• STAGE SPECIFIC AND REGION SPECIFIC EXPRESSION OF INSECT CYTOKINE GBP IN EMBRYO OF CABBAGE ARMYWORM, MAMESTRA BRASSICAE(Biochemistry & Endocrinology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
• Nucleotide Sequences of Genes Encoding Allosamidin-sensitive and -insensitive Chitinases Produced by Allosamidin-producing Streptomyces(Biochemistry & Molecular Biology)
• A Role of Osteoclasts in the Repair Process After Bone Defect with Special Reference to Carbonic Anhydrase
• Effect of in vivo Administration of Thyroid Hormone on Phosphate Uptake of Brush Border Membrane Vesicles from Kidney Cortex of Rachitic Rats
• A New Screening Method for C-P Compound Producing Organisms by the Use of Phosphoenolpyruvate Phosphomutase(Biological Chemistry)
• Cloning and Expression in Escherichia coli of 2-Hydroxypropylphosphonic Acid Epoxidase from the Fosfomycin-producing Organism, Pseudomonas syringae PB-5123
• Nucleotide Sequence of Fortimicin KL1 Methyltransferase Gene Isolated from Micromonospora olivasterospora, and Comparison of Its Deduced Amino Acid Sequence with Those of Methyltransferases Involved in the Biosynthesis of Bialaphos and Fosfomycin
• Synthesis of Novel Amidinato(amidine) Complexes of Molybdenum via Bis(amidine) Complexes
• Molecular Structure of(1R, 8S)-9-Amino-2, 3, 5, 6, 7, 8-hexahydro-1H-cyclopenta[b]quinoline-1,8-diol
• Solution Structure of an Insect Growth Factor Peptide GBP and its EGF Activity
• Structure-antitumor Activity Relationship of Semi-synthetic Spicamycin Derivatives
• Absolute Configuration of Spicamycin, an Antitumor Antibiotic Produced by Streptomyces alanosinicus
• Synthesis and Antitumor Activities of Glycine-exchanged Analogs of Spicamycin
• Structures of New Saponins Isolated from Bupleurum kunmingense Y. Li et S. L. Pan(Organic Chemistry)
• Isolation of Triterpenoid Glycosides (Saikosaponins) from Bupleurum polyclonum Y. Li et S. L. Pan and Their Chemical Structures(Organic Chemistry)
• Reaction Mechanism of a New Glycosyltrehalose-producing Enzyme Isolated from the Hyperthermophilic Archaeum, Sulfolobus solfataricus KM1
• Purification and Characterization of New Trehalose-producing Enzymes Isolated from the Hyperthermophilic Archae, Sulfolobus solfataricus KM1
• Novel C_-Kaurane Type of Diterpene (Oryzalide A), a New Antimicrobial Compound Isolated from Healthy Leaves of a Bacterial Leaf Blight-resistant Cultivar of Rice Plant(Organic Chemistry)
• Facile Reductive Coupling Reaction of Bis(ruthenocenylethynyl)-titanocene Complexes via Visible Light-Activation of the Ruthenocenyl Terminal
• Stachybocins, Novel Endothelin Receptor Antagonists, Produced by Stachybotrys sp.M6222 II.Structure Determination of Stachybocins A, Band C
• Analysis in the course of polydnavirus replication in ovarian calyx cells of the parasitoid wasp, Cotesia kariyai (Hymenoptera: Braconidae)
• Biotransformation of Phenanthrene and 1-Methoxynaphthalene with Streptomyces lividans Cells Expressing a Marine Bacterial Phenanthrene Dioxygenase Gene Cluster(Microbiology & Fermentation Technology)
• Isolation and Structure of Isobutyrylleucanicidin Produced by Streptomyces halstedii
• The Structure of Leucanicidin, a Novel Insecticidal Macrolide Produced by Streptomyces halstedii
• Isolation of Abikoviromycin and Dihydroabikoviromycin as Inhibitors of Polyketide Synthase Involved in Melanin Biosynthesis by Colletotrichum lagenarium
• Isolation and Characterization of 2-Nitroimidazole Produced by Streptomyces Species as an Inhibitor of Both Carbonic Anhydrase and Shell Formation in the Barnacle Balanus amphitrite
• Trichostatin D, a New Inducer of Phenotypic Reversion in Transformed Cells
• Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus
• Detection of the Mevalonate Pathway in Streptomyces Species by Utilization of the 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene
• Carquinostatin B, a New Neuronal Cell-protecting Substance Produced by Streptomyces exfoliatus
• A Novel Neuronal Cell Protecting Substance, Naphthomycinol, Produced by Streptomyces sp. PF7
• A Novel Neuronal Cell Protecting Substance, Espicufolin, Produced by Streptomyces sp. cu39
• Cinnatriacetins A and B, New Antibacterial Triacetylene Derivatives from the Fruiting Biodies of Fistulina hepatica
• New Ravidomycin Analogues, FE35A and FE35B, Apotosis Inducers Produced by Streptomyces rochei
• A Novel Neuronal Cell Protecting Substance, Aestivophoenin C, Produced by Streptomyces purpeofuscus
• 6-Hydroxytetrangulol, a New CPP32 Protease Inducer Produced by Streptomyces sp.
• A Novel Substance with TGF-β like Activity, Diheteropeptin, Produced by a Fungus, Diheterospora sp.
• Isolation and Structure Elucidation of Novel Neuronal Cell Protecting Substances, Carazomadurins A and B Produced by Actinomadura madurae
• Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D II. Physicochemical Properties and Structure Elucidation
• Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D I. Taxonomy, Fermentation, Isolation and Biological Activities
• Diazaphilonic Acid, a New Azaphilone with Telomerase Inhibitory Activity
• A Neuronal Cell Protecting Substance, 4-Demethoxymicigazone, produced by Streptomyces halstedii
• Studies on Cochleamycins, Novel Antitumor Antibiotics II. Physico-chemical Properties and Structure Determination
• Apoptolidin, a New Apoptosis Inducer in Transformed Cells from Nocardiopsis sp.
• Novel Neuronal Cell Protecting Substances, Aestivophoenins A and B, Produced by Streptomyces purpeofuscus
• A New Neuronal Cell Protecting Substance, Lavanduquinocin, Produced by Streptomyces viridochromogenes
• Formobactin, a Novel Radical Scavenging and Neuronal Cell Protecting Substance from Nocardia sp
• Thiopeptide Non-producing Streptomyces Species Carry the tipA Gene : A Clue to Its Function
• Comparison of Two C-P Bond-forming Enzymes Involved in the Biosynthesis of Bialaphos(Biological Chemistry)
• Major Anthocyanin of the Flowers of Hibiscus (Hibiscus rosa-sinensis L.)(Organic Chemistry)
• Growth-phase Dependent Expression of the Mevalonate Pathway in a Terpenoid Antibiotic-producing Streptomyces Strain(Microbiology & Fermentation Technology)
• Cloning of a Gene Cluster Encoding Enzymes Responsible for the Mevalonate Pathway from a Terpenoid-antibiotic-producing Streptomyces Strain(Microbiology & Fermentation Technology)
• The Structure of Enacyloxin II, a Novel Linear Polyenic Antibiotic Produced by Gluconobacter sp. W-315(Organic Chemistry)
• Roridin L, M and Verrucarin M, New Macrocyclic Trichothecene Group Antitumor Antibiotics, from Myrothecium verrucaria
• Fluorinated Blasticidin S(Organic Chemistry)
• Crystal Structure of 1-Deoxy-D-xylulose 5-phosphate Reductoisomerase Complexed with Cofactors : Implications of a Flexible Loop Movement upon Substrate Binding
• IDENTIFICATION AND CLONING OF GROWTH-BLOCKING PEPTIDE (GBP) RECEPTOR(Biochemistry,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• Studies on the Biosynthesis of Terpenoidal Compounds Produced by Actinomycetes 2. Biosynthesis of Carquinostatin B via the Non-mevalonate pathway in Streptomyces exfoliatus
• Construction and Characterization of Escherichia coli Disruptants Defective in the yaeM Gene

もっと見る 閉じる

スポンサーリンク