Diazaphilonic Acid, a New Azaphilone with Telomerase Inhibitory Activity

スポンサーリンク

概要

• 論文の詳細を見る
• 1999-04-25

著者

• SHIN-YA KAZUO

  Institute of Molecular and Cellular Biosciences, The University of Tokyo

• SETO Haruo

  Institute of Molecular and Cellular Biosciences, The University of Tokyo

• Shin-ya Kazuo

  Institute Of Molecular And Cellular Biosciences The University Of Tokyo

• Ikegami Shuji

  Meiji Institute Of Health Science Meiji Milk Products Co. Ltd.

• SAKUMA Sadatoshi

  Meiji Cell Technology Center

• Yaguchi Takashi

  Drug Discovery Pharmaceutical Research Center

• Yaguchi Takashi

  Department Of Applied Chemistry School Of Science And Engineering Waseda University

• Yaguchi Takashi

  Drug Discovery Pharmaceutical Research Center Meiji Seika Kaisha Ltd.

• Sasaki Toru

  Positron Medical Center Tokyo Metropolitan Institute Of Gerontology

• Sasaki T

  Drug Discovery Pharmaceutical Research Center Meiji Seika Kaisha Ltd.

• SASAKI TORU

  Drug Discovery, Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd.

• HOSHIKO SHIGERU

  Drug Discovery, Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd.

• TABATA Yuji

  Drug Discovery, Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd.

• Tabata Yuji

  Drug Discovery Pharmaceutical Research Center

• Hoshiko S

  Meiji Seika Kaisha Ltd. Yokohama Jpn

• Seto Haruo

  Institute Of Molecular And Cellular Biosciences The University Of Tokyo

• Sakuma Sadatoshi

  Meiji Institute Of Health Science Meiji Milk Products Co. Ltd.

• Seto Haruo

  Institute Of Applied Microbiology The University Of Tokyo

• Sasaki Toru

  Drug Discovery Pharmaceutical Research Center Meiji Seika Kaisha Ltd.

関連論文

• Oximidine III, a New Antitumor Antibiotic against Transformed Cells from Pseudomonas sp. II. Structure Elucidation
• Oximidine III, a New Antitumor Antibiotic against Transformed Cells from Pseudomonas sp. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity
• Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neurons from Excitotoxicity : II. Structure Determination
• Selective Cytotoxic Activity of Valinomycin against HT-29 Human Colon Carcinoma Cells via Down-Regulation of GRP78(Pharmacology)
• Structure of Thioviridamide, a Novel Apoptosis Inducer from Streptomyces olivoviridis
• Thioviridamide, a Novel Apoptosis Inducer in Transformed Cells from Streptomyces olivoviridis
• Studies on Terpenoids Produced by Actinomycetes : Isolation and Structural Elucidation of Antioxidative Agents, Naphterpins B and C
• Deoxyverrucosidin, a Novel GRP78/BiP Down-regulator, Produced by Penicillium sp
• Prunustatin A, a Novel GRP78 Molecular Chaperone Down-regulator Isolated from Streptomyces violaceoniger
• Structure of Tyroscherin, an Antitumor Antibiotic against IGF-1-dependent Cells from Pseudallescheria sp
• Byssochlamysol, a New Antitumor Steroid against IGF-1-dependent Cells from Byssochlamys nivea II. Physico-chemical Properties and Structure Elucidation
• Byssochlamysol, a New Antitumor Steroid against IGF-1-dependent Cells from Byssochlamys nivea I, taxonomy, Fermentation, Isolation and Biological Activity
• Structure of Aspochalasin H, a New Member of the Aspochalasin Family
• A Novel Neuronal Cell Protecting Substance, Halxazone, Produced by Streptomyces halstedii
• Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neuronal Cells from Excitotoxicity : I. Fermentation, Isolation, Physico-chemical Properties and Biological Activity
• Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. : II. Physico-chemical Properties and Structure Elucidation
• Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. : I. Production, Isolation and Biological Activity
• Selective Cytotoxicity and Stereochemistry of Aspochalasin D
• Phoenistatin, A New Gene Expression-Enhancing Substance Produced by Acremonium fusigerum
• Rustmicin, a New Macrolide Antibiotic Active Against Wheat Stem Rust Fungus(Organic Chemistry)
• Isolation and Structural Determination of a New Antibiotic Curromycin B
• Spicamycin, a New Differentiation Inducer of Mouse Myeloid Leukemia Cells (Ml) and Human Promyelocytic Leukemia Cells (HL-60)
• Propanosine (K-76), a New Antibiotic Active against Valsa ceratosperma, the Pathogen of Apple Canker Disease
• Taxonomy of Producing Organism, and Production, Isolation, Physico-chemical Properties and Biological Activities of Cirratiomycin A and B
• Phenazostatin C, a New Diphenazine with Neuronal Cell Protecting Activity from Streptomyces sp.
• New Diphenazines with Neuronal Cell Protecting Activity, Phenazostatins A and B, Produced by Streptomyces sp.
• Bacillus subtilis ypgA Gene Is fni, a Nonessential Gene Encoding Type 2 Isopentenyl Diphosphate Isomerase
• Total Synthesis of Spiruchostatin A
• P-286 Total Synthesis of Spiruchostatin A
• Novel Antitumor and Neuroprotective Substances Discovered by Characteristic Screenings Based on Specific Molecular Targets
• Diheteropeptin, a Novel Substance with TGF-β-like Activity, Produced by a Fungus, Diheterospora chlamydosporia : II. Physico-chemical Properties and Structure Elucidation
• Diheteropeptin, a New Substance with TGF-β-like Activity, Produced by a Fungus, Diheterospora chlamydosporia : I. Production, Isolation and Biological Activities
• Structure of a New Anthracycline, Cinerubin Y, Produced by a Blocked Mutant of Streptomyces violaceochromogenes Transformed by pIJ702(Organic Chemistry)
• A New Depsipeptide Antibiotic, Citropeptin(Microbiology & Fermentation Industry)
• A New Depsipeptide Antibiotic, Variapeptin(Microbiology & Fermentation Industry)
• Rasfonin, a New Apoptosis Inducer in ras-dependent Cells from Talaromyces sp.
• Cytovaricin B, a New Inhibitor of JAK-STAT Signal Transduction Produced by Streptomyces torulosus
• Intraspecific Protoplast Fusion of Citric Acid-Producing Strains of Aspergillus niger
• Screening of Microbial Products Modifying the Action of Lepin (Obese Gene Product by a Biosensor)
• Microbial and Chemical Conversion of Antibiotic K-41. I. Isolation and Identification of Conversion Product
• Nucleotide Sequences of Genes Encoding Allosamidin-sensitive and -insensitive Chitinases Produced by Allosamidin-producing Streptomyces(Biochemistry & Molecular Biology)
• Overexpression of Midkine in Pancreatic Duct Adenocarcinomas Induced by N-Nitrosobis(2-oxopropyl)amine in Hamsters and Their Cell Lines
• A New Screening Method for C-P Compound Producing Organisms by the Use of Phosphoenolpyruvate Phosphomutase(Biological Chemistry)
• Cloning and Expression in Escherichia coli of 2-Hydroxypropylphosphonic Acid Epoxidase from the Fosfomycin-producing Organism, Pseudomonas syringae PB-5123
• Nucleotide Sequence of Fortimicin KL1 Methyltransferase Gene Isolated from Micromonospora olivasterospora, and Comparison of Its Deduced Amino Acid Sequence with Those of Methyltransferases Involved in the Biosynthesis of Bialaphos and Fosfomycin
• Absolute Configuration of Spicamycin, an Antitumor Antibiotic Produced by Streptomyces alanosinicus
• Structures of New Saponins Isolated from Bupleurum kunmingense Y. Li et S. L. Pan(Organic Chemistry)
• Isolation of Triterpenoid Glycosides (Saikosaponins) from Bupleurum polyclonum Y. Li et S. L. Pan and Their Chemical Structures(Organic Chemistry)
• Stachybocins, Novel Endothelin Receptor Antagonists, Produced by Stachybotrys sp.M6222 II.Structure Determination of Stachybocins A, Band C
• Isolation and Structure of Isobutyrylleucanicidin Produced by Streptomyces halstedii
• The Structure of Leucanicidin, a Novel Insecticidal Macrolide Produced by Streptomyces halstedii
• Trichostatin D, a New Inducer of Phenotypic Reversion in Transformed Cells
• Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus
• Detection of the Mevalonate Pathway in Streptomyces Species by Utilization of the 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene
• γ-Linolenic Acid Production by a Low Temperature-Resistant Mutant of Mortierella ramanniana
• Carquinostatin B, a New Neuronal Cell-protecting Substance Produced by Streptomyces exfoliatus
• A Novel Neuronal Cell Protecting Substance, Naphthomycinol, Produced by Streptomyces sp. PF7
• A Novel Neuronal Cell Protecting Substance, Espicufolin, Produced by Streptomyces sp. cu39
• Cinnatriacetins A and B, New Antibacterial Triacetylene Derivatives from the Fruiting Biodies of Fistulina hepatica
• New Ravidomycin Analogues, FE35A and FE35B, Apotosis Inducers Produced by Streptomyces rochei
• A Novel Neuronal Cell Protecting Substance, Aestivophoenin C, Produced by Streptomyces purpeofuscus
• 6-Hydroxytetrangulol, a New CPP32 Protease Inducer Produced by Streptomyces sp.
• A Novel Substance with TGF-β like Activity, Diheteropeptin, Produced by a Fungus, Diheterospora sp.
• Isolation and Structure Elucidation of Novel Neuronal Cell Protecting Substances, Carazomadurins A and B Produced by Actinomadura madurae
• Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D II. Physicochemical Properties and Structure Elucidation
• Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D I. Taxonomy, Fermentation, Isolation and Biological Activities
• Improvement of Docosahexaenoic Acid Production in a Culture of Thraustochytrium aureum by Medium Optimization
• Grouping Newly Isolated Docosahexaenoic Acid-Producing Thraustochytrids Based on Their Polyunsaturated Fatty Acid Profiles and Comparative Analysis of 18S rRNA Genes
• PF1163A and B, New Antifungal Antibiotics Produced by Penicillium sp. : I. Taxonomy of Producing Strain, Fermentation, Isolation and Biological Activities
• PF1092A, B and C, New Nonsteroidal Progesterone Receptor Ligands Produced by Penicillium oblatum I. Taxonomy of Producing Strain, Fermentation, Isolation and Biological Activities
• Use of a Glycoprotein gB Promoter for Expression of Genes Inserted into the Human Cytomegalovirus Genome
• Diazaphilonic Acid, a New Azaphilone with Telomerase Inhibitory Activity
• A Neuronal Cell Protecting Substance, 4-Demethoxymicigazone, produced by Streptomyces halstedii
• Apoptolidin, a New Apoptosis Inducer in Transformed Cells from Nocardiopsis sp.
• Midkine Rescues Wilms' Tumor Cells from Cisplatin-Induced Apoptosis: Regulation of Bcl-2 Expression by Midkine^1
• Novel Neuronal Cell Protecting Substances, Aestivophoenins A and B, Produced by Streptomyces purpeofuscus
• A New Neuronal Cell Protecting Substance, Lavanduquinocin, Produced by Streptomyces viridochromogenes
• Formobactin, a Novel Radical Scavenging and Neuronal Cell Protecting Substance from Nocardia sp
• Thiopeptide Non-producing Streptomyces Species Carry the tipA Gene : A Clue to Its Function
• Comparison of Two C-P Bond-forming Enzymes Involved in the Biosynthesis of Bialaphos(Biological Chemistry)
• Major Anthocyanin of the Flowers of Hibiscus (Hibiscus rosa-sinensis L.)(Organic Chemistry)
• Growth-phase Dependent Expression of the Mevalonate Pathway in a Terpenoid Antibiotic-producing Streptomyces Strain(Microbiology & Fermentation Technology)
• Cloning of a Gene Cluster Encoding Enzymes Responsible for the Mevalonate Pathway from a Terpenoid-antibiotic-producing Streptomyces Strain(Microbiology & Fermentation Technology)
• The Structure of Enacyloxin II, a Novel Linear Polyenic Antibiotic Produced by Gluconobacter sp. W-315(Organic Chemistry)
• Neosartorya sublevispora, a new species of soil-borne Eurotiales
• Talaromyces euchlorocarpius, a new species from soil
• Microsphaeropsis rugospora, a new species from Japanese soil
• Isolation of Roumegueriella rufula as a new record from East Asia
• A new species of Lasiobolidium from Californian soil
• New and rare microfungi from the island of Hachijo-jima
• A reappraisal of intrageneric classification of Talaromyces based on the ubiquinone systems
• Aspergillus taichungensis, a new species from Taiwan
• Fluorinated Blasticidin S(Organic Chemistry)
• Synthesis and Characterization of Highly Pure Form of Sodium Salt of Anionic, Thiomalatogold (I) Complex with Antiarthritic Activity. Analogs of Anionic, Thiomalatosilver (I) Complex with Antimicrobial Activity
• Crystal Structure of 1-Deoxy-D-xylulose 5-phosphate Reductoisomerase Complexed with Cofactors : Implications of a Flexible Loop Movement upon Substrate Binding
• Studies on the Biosynthesis of Terpenoidal Compounds Produced by Actinomycetes 2. Biosynthesis of Carquinostatin B via the Non-mevalonate pathway in Streptomyces exfoliatus
• Construction and Characterization of Escherichia coli Disruptants Defective in the yaeM Gene
• Anguinomycins C and D, New Antitumor Antibiotics with Selective Cytotoxicity against Transformed Cells
• Isolation and Structural Elucidation of Antioxidative Substances, Carbazoquinocins A to F
• Nerfilin I, a Novel Microbial Metabolite Inducing Neurite Outgrowth of PC12 Cells

もっと見る 閉じる

スポンサーリンク