Promoinducin, a Novel Thiopeptide Produced by Streptomyces sp. SF2741
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概要
- 論文の詳細を見る
Our continued screening to find tipA promoter-inducing substances resulted in the isolation of promoinducin from a mycelial extract of Streptomyces sp. SF2741. Based on various 1D- and 2D-NMR studies, including field gradient (FG)-COSY, HSQC, FG-HMBC, phase-sensitive ^<13>C-decoupled HMBC and NOESY experiments, promoinducin's structure was established to be a thiopeptide composed of threonine, some unusual amino acids masked at their carboxyl groups by thiazole or methyloxazole rings, sulfomycinamate and five dehydroalanine residues. Promoinducin induced the tipA promoter at 40ng/ml, and also exhibited strong antibacterial activity against some Gram-positive bacteria.
- 社団法人日本農芸化学会の論文
- 1995-05-23
著者
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Yun B‐s
Functional Metabolomics Research Center Korea Research Institute Of Bioscience And Biotechnology
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Yun Bong-sik
Functional Metabolites Research Center Kribb
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Yun Bong-sik
Institute Of Molecular And Cellular Biosciences The University Of Tokyo
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Yun Bong-sik
Korea Research Institute Of Bioscience And Biotechnology Kist. Yusong
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Yun Bong-sik
Functional Metabolomics Research Center Korea Research Institute Of Bioscience And Biotechnology
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Yun B‐s
Korea Res. Inst. Biosci. And Biotechnol. Taejon Kor
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Seto Haruo
Institute Of Applied Microbiology The University Of Tokyo
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