ミンクのアリューシャン病に対するコルソン投与実験

概要

論文の詳細を見る
We tried the experimental treatment of corson, a synthetic adrenocortical steroid, for the two minks affected with Aleutian disease shown remarkable hyper-γ-globulinemia. The results are as follows : 1. The most striking change in autopsy was a marked atrophy of the systemic lymph nodes, and in the histological examination plasma cells were shown to degenerate to a karyolysis, karyorrhexis, swelling of the cytoplasm and lower affinity to staining dye and the tightly infiltrated areas of plasma cell in the lymph nodes were replaced with roughly finding as a result of falling off them. 2. γ-globulin in the serum, especially 7 S-γ fraction, decreased greatly. 3. The above findings in any case are thought to be an effect of the administrated drug and it is suggested that corson may be an inhibitic action for the plasma cell.
帯広畜産大学の論文
1969-09-30