Effect of Salithion Enantiomers on Larval Growth, Carbohydrases, Acetylcholinesterase, Adenylate Cyclase Activities and Cyclic Adenosine 3',5'-monophosphate Level of Musca domestica and Tribolium castaneum(Pesticide Chemistry)
スポンサーリンク
概要
- 論文の詳細を見る
Dietary (R)(+)-salithion was a more potent insecticide (LC_<50>=9.3 ppm) than the (S)(-)-enantiomer (LC_<50>=63 ppm), correlating acetylcholinesterase (AChE) inhibition in vivo (I_<50>=7.7 and 63 ppm) against Tribolium castaneum larvae. (S)(-)-Salioxon derived from (R)(+)-salithion had a stronger inhibitory activity (I_<50>=8.8 μM) than the (R)(+)-enantiomer (I_<50>=22 μM) in vitro against larval AChE. However, against Musca domestica female adults, a reversed tendency was observed: (S)(-)-salithion and (R)(+)-salioxon were more potent than (R)(+)-salithion and (S)(-)-salioxon in topical insecticidal and anticholinesterase activities in vivo and in vitro, respectively. Hence, the reversed stereospecificity between the T. castaneum larvicidal and M. domestica insecticidal activities of salithion enantiomers is due to a stereospecific difference in the intrincic potency of salioxon enantiomers as an AChE inhibitor with the two insects. A suppression of M. domestica larval growth, gut amylase and invertase activities by dietary 0.5, 1.0 and 1.25 ppm of (S)(-)-salithion was observed 2 days after treatment. A similar tendency was recognized when 1.25 and 2.50 ppm of (R)(+)-salithion was used. However, against M. domestica female adults, no appreciable effect on these enzymes was recognized 1-72 hr after topical application of 0.05 and 0.10 μg/fly of (S)(-)-salithion, and 0.01 and 0.05 μM/fly of (R)(+)-salithion. The whole-body levels of cyclic adenosine 3',5'-monophosphate (cAMP) were slightly increased in T. castaneum larvae 3 days after a dietary 60 and 80 ppm of (S)(-)-salithion treatment, and in M. domestica larvae 2 days after treating by dietary 1.25 and 2.50 ppm of (R)(+)-salithion, respectively. Neither of the enantiomers of salithion activated adenylate cyclase prepared from Periplaneta americana ventral nerve cords, but suppressed octopamine potency, suggesting that salithion could act as an antagonist to the octopamine-receptor and that the increased level of whole-body cAMP could be due to the inhibition of phosphodiesterase.
- 社団法人日本農芸化学会の論文
- 1990-04-23
著者
-
Koga Hiroaki
Department Of Orthopaedic Surgery Imakiire General Hospital
-
Koga Hiroaki
Department Of Agricultural Chemistry Kyushu University:(present Office)nagase Ind. K.k.
-
ETO Morifusa
Department of Agricultural Chemistry, Kyushu University
-
HIRASHIMA Akinori
Department of Agricultural Chemistry, Kyushu University
-
UENO Ryohei
Department of Agricultural Chemistry, Kyushu University
-
OYAMA Kazuhiko
Department of Agricultural Chemistry, Kyushu University
-
Ueno Ryohei
Department Of Ocean Sciences Tokyo University Of Marine Science And Technology
-
Ueno Ryohei
Department Of Agricultural Chemistry Kyushu University
-
Eto Morifusa
Department Of Agricultural Chemistry Kyushu University
-
Oyama Kazuhiko
Department Of Agricultural Chemistry Kyushu University:(present Office)pharmaceutical Research Labor
-
Hirashima A
Department Of Applied Genetics And Pest Management Faculty Of Agriculture Graduate School Kyushu Uni
-
Hirashima Akinori
Department Of Agricultural Chemistry Kyushu University
-
Eto Morifusa
Department Of Agricultural Chemistry Faculty Of Agriculture Kyushu University
関連論文
- An atypical extrahepatic metastasis of the distal phalanx from hepatocellular carcinoma
- Ossification of the posterior longitudinal ligament in dizygotic twins with schizophrenia : a case report
- Quality of Life in Elderly Patients With Ossification of the Posterior Longitudinal Ligament
- Gender-specific haplotype association of collagen α2 (XI) gene in ossification of the posterior longitudinal ligament of the spine
- Recent progress in the study of pathogenesis of ossification of the posterior longitudinal ligament
- Repulsion-Induced Order Formation in Graphite-Diamondlike Transition of Boron Nitride : A Molecular Dynamics Study (Condensed Matter: Structure, Mechanical and Thermal Properties)
- Multistage Order-Disorder Surface Transition of Si(111)√3×√3-Ag Surface with Defects(Condensed Matter : Structure, Mechanical and Thermal Properties)
- Multistage Order-Disorder Surface Transition of Si(111)√×√-Ag Surface with Defects
- Effects of Some Anti-Juvenile Hormone Agents (Precocene-2, J-2710, KK-110) on Postembryonic Development of Neobellieria bullata(Pesticide Chemistry)
- Effect of Salithion Enantiomers on Larval Growth, Carbohydrases, Acetylcholinesterase, Adenylate Cyclase Activities and Cyclic Adenosine 3',5'-monophosphate Level of Musca domestica and Tribolium castaneum(Pesticide Chemistry)
- Epitaxial Growth of Cubic BN on Diamond : An Ab Initio Study
- Migration-Enhanced Epitaxy of Cubic BN : An Ab Initio Study
- Facial Schwannoma Spreading into the Middle Cranial Fossa and the Cerebellopontine Angle : Case Report
- B309 フェロモン分泌阻害剤の pharmacophore モデリング
- Synthesis and Octopaminergic Agonist Activity of 2-(Substituted benzylamino)-2-thiazolines
- Synthesis and Biological Activity of 2-Aminothiazolines and 2-Mercaptothiazolines as Octopaminergic Agonists(Pesticide Chemistry)
- Root Growth-promoting Activities of N-Acyl-L-proline Derivatives
- Interstitial Radiofrequency Hyperthermia for Brain Tumors : Preliminary Laboratory Studies and Clinical Application
- Sense of Virtual Reality : Effectiveness of Replacing 3D Imagery with 2D/3D Hybrid Imagery(Cyberworlds)
- Results of a Longer Than 10-Year Follow-Up of Patients With Rheumatoid Arthritis Treated by Occipitocervical Fusion
- Metabolic Formation of 4-Methy-4H-1, 3, 2-benzodioxaphosphorins from Bis(o-ethylphenyl) Phenylphosphonates in House Flies(Pesticide Chemistry)
- Optimization of Heterotrophic Culture Conditions for n-Alkane Utilization and Phylogenetic Position Based on the 18S rDNA Sequence of a Thermotolerant Prototheca zopfii Strain
- Effect of temperature and cell density on ethanol fermentation by a thermotolerant aquatic yeast strain isolated from a hot spring environment
- Characterization of thermotolerant, fermentative yeasts from hot spring drainage
- Studies on the Mechanisms of Organophosphate Resistance in Oriental Houseflies, Musca domestica vicina MACQUART. (Diptera : Muscidae)
- Synergetic effects of cell immobilization in polyurethane foam and use of thermotolerant strain on degradation of mixed hydrocarbon substrate by Prototheca zopfii
- Carbohydrate Enzymes in House Fly Musca domestica Larvae : Biochemical Properties and Toxicological Significance
- Potency of Isomers of 8-Isopropyl-6-oxabicyclo[3.2.1]octan-7-one at the Picrotoxinin Binding Site in the GABA-Gated Chloride Channel in Rat Brain
- Threshold Size for Precocious Metamorphosis by an Anti-Juvenile Hormone in Silkworm Larvae, Bombyx mori L.
- Precocious Metamorphosis Induced by an Anti-Juvenile Hormone Compound Applied to 3rd Instar Silkworm Larvae, Bombyx mori L. (Lepidoptera : Bombycidae)
- Anti-Juvenile Hormone Activity of Imidazole Compound (KK-22) and Its Diminution by Methoprene in the 4th Instar Silkworm, Bombyx mori L. : Lepidoptera : Bombycidae
- Anti-Juvenile Hormone Activity of 1-Citronellyl-5-phenylimidazole in the 3rd Instar Silkworm, Bombyx mori L.(Lepidoptera : Bombycidae)
- Synthesis and Insecticidal Activity of Bicyclic Phosphorothionates and Related Monocyclic Phosphorothionates
- Synthesis and Insecticidal Activity of Oxazaphospholidines, Oxathiaphospholanes, and Thiazaphospholidines(Pesticide Chemistry)
- Synthesis of Optically Active 1,3,2-Oxazaphospholidine 2-Sulfides and 1,3,2-Benzodioxaphosphorin 2-Sulfides(Organic Chemistry)
- Regulation of bombykol production by tyramine and octopamine in Bombyx mori
- Synthesis and Octopaminergic-agonist Activity of 3-(Substituted Phenyl) imidazolidine-2-thiones and Related Compounds
- Effects of a Muscarinic Agonist on Octopamine-stimulated Cyclic AMP Production in American Cockroach (Periplaneta americana) Nerve Cords(Biological Chemistry)
- Synthesis and Bleaching Activity of 1,5-Disubstituted Imidazoles
- Chemical Reactivity of Oxidation Products of the Dithiolanylidenemalonate Fungicide, Isoprothiolane
- Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire Investigation in Healthy Volunteers
- Stress-induced Changes in the Biogenic Amine Levels and Larval Growth of Tribolium castaneum Herbst
- Anti-Ecdysteroid Action of Some Imidazole Derivatives on Pupal-Adult Development of the Silkworm, Bombyx mori : Lepidoptera : Bombycidae
- Effects of Methoprene and 20-Hydroxyecdysone on the Precocious Metamorphosis Induced by 1,5-Disubstituted Imidazoles
- Syntheses and Biological Activities of Some Dithiolanylidenemalonate Derivatives and Related Compounds
- Chlorosis-inducing Activity of 1-Alkyl-5-phenylimidazoles
- Synthesis and Insect Growth Regulatory Activity of 1,5-Disubstituted Imidazoles with Non-terpene Chains(Pesticide Chemistry)
- Effects of 1,5-Disubstituted Imidazoles on the Growth of Lettuce and Rice Seedlings
- Synthesis and Plant Growth Regulatory Activity of 1,5-Disubstituted Imidazoles
- Lethal Disturbances in the Pre-ecdysial Processes of Sarcophaga bullata Caused by Imidazole Containing KK-42(Pesticide Chemistry)
- Effects of Anti Juvenile Hormones and Related Compounds on Development in the Larvae of Bombyx mori
- Induction of Precocious Metamorphosis by 1,5-Disubstituted Imidazoles with a Non-terpene Chain(Pesticide Chemistry)
- Characteristics of Houseflies Selected by Fenitrothion and Diethyl Fenitrothion (Pesticide Chemistry)
- Termination of Egg Diapause by Imidazoles in the Silkmoth, Antheraea yamamai(Pesticide Chemistry)
- Synthesis of Two Optical Isomers of the Insect Anti-juvenile Hormone Agent Fluoromevalonolactone (FMev) and Their Biological Activities(Organic Chemistry)
- Anti-juvenile Hormone Effects of an Imidazole Compound (KK-42) in Different Larval Instars of Bombyx mori
- Ethanolysis of Substituted 2-Ethoxy-1,3,2-oxazaphospholidine and -thiazaphospholidine Oxides Monitored by ^P-NMR as a Model for Interaction with Acetylcholinesterase
- Synthesis and Octopaminergic-agonist Activity of 2-(Arylimino)thiazolidines, 2-(Aralkylamino)-2-thiazolines, and Related Compounds
- Ecdysteroids in Stress Responsive and Nonresponsive Drosophila Virilis Lines under Stress Conditions
- Biogenic Amines in Drosophila virilis under Stress Conditions
- Biogenic Amines in Periplaneta americana L.: Accumulation of Octopamine, Synephrine, and Tyramine by Stress
- Binding of Toxic Bicyclic Phosphates to Rat Brain Synaptic Membrane Fractions
- Migration-Enhanced Epitaxy of Cubic BN: An Ab Initio Study
- Small Fermi Pocket in Layered Organic Superconductor \beta-(BDA-TTP)2SbF6
- Synthesis of Highly Pure Enantiomers of the Insecticide Salithion
- Stress Oscillations in Co-Solvent Nanoparticle–Polymer Suspensions Subjected to Constant Shear Rate
- An Imidazole Compound as a Potent Anti-ecdysteroid in an Insect
- Terpenoid Imidazoles : New Anti-juvenile Hormones
- Insecticidal Benzimidazoles with a Terpenoid Moiety
- Effects of Insect-Growth-Regulatory Benzimidazole Derivatives on Cultured Integument of the Rice Stem Borer and Mitochondria from Rat Liver
- Molecular Structure and Conformation of 4H-l, 3, 2-Benzodioxaphosphorins, Including the Insecticide Salithion
- Synthesis and And-Juvenile Hormone Activity of 1-Substituted-5-[(E)-2, 6-dimethyl-1, 5-heptadienyl]imidazoles
- The Use of a Tribalium Chitin Synthetase Assay in Studying the Effects of Benzimidazoles with a Terpene Moiety and Related Compounds
- Synthesis and Anti-juvenile Hormone Activity of 1-Citronellyl-5-substituted Imidazoles
- Biological Activity of Optically Active Salithion and Salioxon
- Synthesis and Insecticidal Activity of Optically Active 2-Methoxy-5-phenyl-1, 3, 2-oxazaphospholidine 2-Sulfide
- Studies on Insect Growth Regulating Substances with Insect Cell Cultures
- Synthesis and Some Spectral Characteristics of Bicyclic Phosphate, GABA Antagonists
- Synthesis and Biological Activity of 0, 0-Dialkyl S-(5-Aryl-1, 3, 4-oxadiazol-2(3H)-on-3-yl)methyl Phosphorothioates and Phosphorodithioates
- Stereochemistry and Reactions of Aziridinylphosphinothionates Derived from Amino Acids
- Reaction of Toxic Bicyclic Phosphates with Acetylcholinesterases and α-Chymotrypsin
- Bicyclic Phosphate Binding to Cyclodextrin: A Receptor Model
- Stereochemistry of Aryl Methyl Phosphorochloridothionates as Chiral Two-step Phosphorylating Reagents
- Glutathione-dependent Degradation of Organophosphate Insecticides by Organophosphate-susceptible and Resistant Housefly Abdomen Homogenates