Metabolic Formation of 4-Methy-4H-1, 3, 2-benzodioxaphosphorins from Bis(o-ethylphenyl) Phenylphosphonates in House Flies(Pesticide Chemistry)

スポンサーリンク

概要

• 論文の詳細を見る

• Bis(4-chloro-2-ethylphenyl) phenylphosphonate was metabolically transformed into the corresponding cyclic ester, i.e., 6-chloro-4-methyl-2-phenyl-4H-1,3,2-benzodioxaphosphorin 2-oxide, in houseflies in vivo. In a p-unsubstituted analog, hydroxylation at the para-position of an ester linkage occurred preferably to alpha-hydroxylation with subsequent cyclization. The cyclization was diastereomerically selective, giving predominantly the cis ester. The biological activities of synthesized and related cyclic esters were similar to but weaker than saligenin cyclic phosphorus esters lacking a methyl group at the 4-position.

• 社団法人日本農芸化学会の論文
• 1987-11-23

著者

• ITO Shigekazu

  Department of Chemistry, Graduate School of Science, Tohoku University

• Ito Shigekazu

  Department Of Agricultural Chemistry Kyusyu University:(present Office)k・i Chemical Research Institu

• ETO Morifusa

  Department of Agricultural Chemistry, Kyushu University

• Wu Shao-yong

  Department Of Agricultural Chemistry Kyusyu University

• Eto Morifusa

  Department Of Agricultural Chemistry Kyushu University

• Eto Morifusa

  Department Of Agricultural Chemistry Faculty Of Agriculture Kyushu University

関連論文

• Improved Preparative Method for 1,2-Diaryl-3,4-diphosphinidenecyclobutenes and Its Application to the Studies of 1,2-Bis(arylthienyl)-3,4-diphosphinidenecyclobutenes
• Preparation of Some Mutifunctionalized Methylenephosphines by Reactions of Cholro[(2,4,6-tri-t-butylphenyl)phosphinidene]methyllithiums with Carbonyl Compounds
• Preparation and Structure of 2,3-Dichloro-1,4-bis(2,4,6-tri-t-butylphenyl)-1,4-diphospha-1,3-butadiene
• Effects of Some Anti-Juvenile Hormone Agents (Precocene-2, J-2710, KK-110) on Postembryonic Development of Neobellieria bullata(Pesticide Chemistry)
• Effect of Salithion Enantiomers on Larval Growth, Carbohydrases, Acetylcholinesterase, Adenylate Cyclase Activities and Cyclic Adenosine 3',5'-monophosphate Level of Musca domestica and Tribolium castaneum(Pesticide Chemistry)
• B309 フェロモン分泌阻害剤の pharmacophore モデリング
• A Case of Asymptomatic Submucosal-Type Leiomyoma of the Urinary Bladder Correctly Diagnosed with Magnetic Resonance Imaging (MRI) and Successfully Treated by Transurethral Resection
• Synthesis and Octopaminergic Agonist Activity of 2-(Substituted benzylamino)-2-thiazolines
• Synthesis and Biological Activity of 2-Aminothiazolines and 2-Mercaptothiazolines as Octopaminergic Agonists(Pesticide Chemistry)
• Oxidation of 1,3-Diphosphacyclobutane-2,4-diyl with Ammoniumyl Antimonate and EPR Study of the Corresponding Cation Radical
• The Phenylthio Group as a New Substituent on the 2-Position of Sterically Protected 1-Phosphaethenes
• Root Growth-promoting Activities of N-Acyl-L-proline Derivatives
• Metabolic Formation of 4-Methy-4H-1, 3, 2-benzodioxaphosphorins from Bis(o-ethylphenyl) Phenylphosphonates in House Flies(Pesticide Chemistry)
• An Efficient Synthetic Method of 1-(2, 4, 6-Tri-t-butylphenyl)-3-phenyl-1-phosphaallenes [Mes^*P=C=CR-Ph ; R = H, SiMe_3] from Dibromophosphaethene [Mes^*P=CBr_2] (Mes^* = 2, 4, 6-t-Bu_3C_6H_2)
• Demonstrations of NMR Quantum Information Processing Utilizing ^P Nuclei of Phosphorus Heterocycles
• Preparation and Properties of Kinetically Stabilized Phosphaethene Derivatives Carrying the Methylsulfanyl Group
• Copper-mediated Coupling Reaction of Kinetically Stabilized 1-Methyl-2-phosphaethenyllithiums Involving an Isomerization to a 3-Phospha-2-propenyllithium Derivative^1
• Studies on the Mechanisms of Organophosphate Resistance in Oriental Houseflies, Musca domestica vicina MACQUART. (Diptera : Muscidae)
• Carbohydrate Enzymes in House Fly Musca domestica Larvae : Biochemical Properties and Toxicological Significance
• Potency of Isomers of 8-Isopropyl-6-oxabicyclo[3.2.1]octan-7-one at the Picrotoxinin Binding Site in the GABA-Gated Chloride Channel in Rat Brain
• Threshold Size for Precocious Metamorphosis by an Anti-Juvenile Hormone in Silkworm Larvae, Bombyx mori L.
• Precocious Metamorphosis Induced by an Anti-Juvenile Hormone Compound Applied to 3rd Instar Silkworm Larvae, Bombyx mori L. (Lepidoptera : Bombycidae)
• Anti-Juvenile Hormone Activity of Imidazole Compound (KK-22) and Its Diminution by Methoprene in the 4th Instar Silkworm, Bombyx mori L. : Lepidoptera : Bombycidae
• Anti-Juvenile Hormone Activity of 1-Citronellyl-5-phenylimidazole in the 3rd Instar Silkworm, Bombyx mori L.(Lepidoptera : Bombycidae)
• Synthesis and Insecticidal Activity of Oxazaphospholidines, Oxathiaphospholanes, and Thiazaphospholidines(Pesticide Chemistry)
• Synthesis of Optically Active 1,3,2-Oxazaphospholidine 2-Sulfides and 1,3,2-Benzodioxaphosphorin 2-Sulfides(Organic Chemistry)
• Synthesis and Octopaminergic-agonist Activity of 3-(Substituted Phenyl) imidazolidine-2-thiones and Related Compounds
• Effects of a Muscarinic Agonist on Octopamine-stimulated Cyclic AMP Production in American Cockroach (Periplaneta americana) Nerve Cords(Biological Chemistry)
• Synthesis and Bleaching Activity of 1,5-Disubstituted Imidazoles
• Chemical Reactivity of Oxidation Products of the Dithiolanylidenemalonate Fungicide, Isoprothiolane
• Stress-induced Changes in the Biogenic Amine Levels and Larval Growth of Tribolium castaneum Herbst
• Anti-Ecdysteroid Action of Some Imidazole Derivatives on Pupal-Adult Development of the Silkworm, Bombyx mori : Lepidoptera : Bombycidae
• Effects of Methoprene and 20-Hydroxyecdysone on the Precocious Metamorphosis Induced by 1,5-Disubstituted Imidazoles
• Syntheses and Biological Activities of Some Dithiolanylidenemalonate Derivatives and Related Compounds
• Chlorosis-inducing Activity of 1-Alkyl-5-phenylimidazoles
• Synthesis and Insect Growth Regulatory Activity of 1,5-Disubstituted Imidazoles with Non-terpene Chains(Pesticide Chemistry)
• Effects of 1,5-Disubstituted Imidazoles on the Growth of Lettuce and Rice Seedlings
• Synthesis and Plant Growth Regulatory Activity of 1,5-Disubstituted Imidazoles
• Lethal Disturbances in the Pre-ecdysial Processes of Sarcophaga bullata Caused by Imidazole Containing KK-42(Pesticide Chemistry)
• Effects of Anti Juvenile Hormones and Related Compounds on Development in the Larvae of Bombyx mori
• Induction of Precocious Metamorphosis by 1,5-Disubstituted Imidazoles with a Non-terpene Chain(Pesticide Chemistry)
• Characteristics of Houseflies Selected by Fenitrothion and Diethyl Fenitrothion (Pesticide Chemistry)
• Termination of Egg Diapause by Imidazoles in the Silkmoth, Antheraea yamamai(Pesticide Chemistry)
• Synthesis of Two Optical Isomers of the Insect Anti-juvenile Hormone Agent Fluoromevalonolactone (FMev) and Their Biological Activities(Organic Chemistry)
• Anti-juvenile Hormone Effects of an Imidazole Compound (KK-42) in Different Larval Instars of Bombyx mori
• Transmetallation Reaction of 1-Phenylthio- or 1-Tolylthio-2-(2,4,6-tri-t-butylphenyl)-2-phosphathenyllithium with Copper(II) and Mercury(II)
• Ethanolysis of Substituted 2-Ethoxy-1,3,2-oxazaphospholidine and -thiazaphospholidine Oxides Monitored by ^P-NMR as a Model for Interaction with Acetylcholinesterase
• Synthesis and Octopaminergic-agonist Activity of 2-(Arylimino)thiazolidines, 2-(Aralkylamino)-2-thiazolines, and Related Compounds
• Biogenic Amines in Periplaneta americana L.: Accumulation of Octopamine, Synephrine, and Tyramine by Stress
• Binding of Toxic Bicyclic Phosphates to Rat Brain Synaptic Membrane Fractions
• Synthesis of Highly Pure Enantiomers of the Insecticide Salithion
• An Imidazole Compound as a Potent Anti-ecdysteroid in an Insect
• Terpenoid Imidazoles : New Anti-juvenile Hormones
• Insecticidal Benzimidazoles with a Terpenoid Moiety
• Effects of Insect-Growth-Regulatory Benzimidazole Derivatives on Cultured Integument of the Rice Stem Borer and Mitochondria from Rat Liver
• Molecular Structure and Conformation of 4H-l, 3, 2-Benzodioxaphosphorins, Including the Insecticide Salithion
• Synthesis and And-Juvenile Hormone Activity of 1-Substituted-5-[(E)-2, 6-dimethyl-1, 5-heptadienyl]imidazoles
• The Use of a Tribalium Chitin Synthetase Assay in Studying the Effects of Benzimidazoles with a Terpene Moiety and Related Compounds
• Synthesis and Anti-juvenile Hormone Activity of 1-Citronellyl-5-substituted Imidazoles
• Biological Activity of Optically Active Salithion and Salioxon
• Synthesis and Insecticidal Activity of Optically Active 2-Methoxy-5-phenyl-1, 3, 2-oxazaphospholidine 2-Sulfide
• Studies on Insect Growth Regulating Substances with Insect Cell Cultures
• Synthesis and Some Spectral Characteristics of Bicyclic Phosphate, GABA Antagonists
• Synthesis and Biological Activity of 0, 0-Dialkyl S-(5-Aryl-1, 3, 4-oxadiazol-2(3H)-on-3-yl)methyl Phosphorothioates and Phosphorodithioates
• Stereochemistry and Reactions of Aziridinylphosphinothionates Derived from Amino Acids
• Reaction of Toxic Bicyclic Phosphates with Acetylcholinesterases and α-Chymotrypsin
• Bicyclic Phosphate Binding to Cyclodextrin: A Receptor Model
• Stereochemistry of Aryl Methyl Phosphorochloridothionates as Chiral Two-step Phosphorylating Reagents
• Preparation of optically active piperazines from ethyl (S)-2-(2-alkyl-1-aziridinyl)acetates.
• Glutathione-dependent Degradation of Organophosphate Insecticides by Organophosphate-susceptible and Resistant Housefly Abdomen Homogenates

もっと見る 閉じる

スポンサーリンク