Effect of Dietary Protein Levels on the Urinary Excretion of Nicotinamide and Its Metabolites in Rats(Food & Nutrition)
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概要
- 論文の詳細を見る
Male rats of the Wistar strain (seven weeks old) were fed ad libitum with a 10%, 20% or 40% casein diet (these diets contained sufficient nitocinic acid of 6 mg per 100g of diet) for 20 days. Urine was collected for the last 2 days, and the urinary excretion of nicotinamide, N^1-methylnicotinamide (MNA), N^1-methyl-2-pyridone-5-carboxamide (2-py) and N^1-methylnicotinamide (4-py) was measured using the most reliable determination methods with a high-performance liquid chromatograph. The urinary excretion of nicotinamide and 2-py was about the same in the three groups. The urinary excretion of 4-py increased with increasing dietary protein levels, contrary to MNA, which decreased with increasing dietary protein levels. The total urinary excretion of nicotinamide, MNA, 2-py and 4-py was about the same amount in the three groups. The contents of total nicotinamide and MNA in the liver decreased with increasing dietary protein levels, all these results being inconsistent with the etablished theory.
- 社団法人日本農芸化学会の論文
- 1988-07-23
著者
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Iwai Kazuo
Laboratory Of Nutrition Chemistry Faculty Of Home Economics Kobe Women's University
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Shibata Katsumi
Laboratories Of Food Science And Nutrition Department Of Life Style Studies School Of Human Cultures
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Iwai Kazuo
Laboratory Of Nutritional Chemistry Department Of Food Science And Technology Faculty Of Agriculture
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NOMAMOTO Rika
Laboratory of Nutritional Biochemistry, Department of Food Science and Nutrition, Faculty of Domesti
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Nomamoto Rika
Laboratory Of Nutritional Biochemistry Department Of Food Science And Nutrition Faculty Of Domestic
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Shibata Katsumi
Laboratory Of Nutritional Biochemistry Department Of Food Science And Nutrition Faculty Of Domestic
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