Tissue Distribution of the Enzymes Concerned with the Biosynthesis of NAD in Rats(Biological Chemistry)

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概要

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• There are three NAD biosynthetic pathways: the nicotinic acid-NAD, nicotinamide-NAD, and quinolinic acid (dericed from tryptohan)-NAD pathways. To discover the main pathways of NAD biosyntheses in various tissues of the rat, the tissue distribution of nicotinamidase, quinolinate phosphoribosyltransferase, niconinate phosphoribosyltransferase, nicotinamide phosphoribosyltransferase, nicotinamide mononucleotiba adenylyltransferase, and NAD^+ synthetase were investigated. All of the tissues could synthesize NAD from niconinamide, judging from that the activities of nicotinamide phosphoribosyltransferase and NMN adenylyltransferase detected in all of the tissues. From nicotinic acid, only liver, kidneys, and heart could. Liver and kidney can also synthesize NAD de novo from quinolinic acid.

• 社団法人日本農芸化学会の論文
• 1986-12-23

著者

• Shibata K

  Teikoku Women's Univ. Osaka Jpn

• Seto Koji

  Biotechnology Research Laboratory Tosoh Co. Ltd.

• Iwai K

  Kyoto Univ. Kyoto

• Iwai K

  Department Of Food Science And Technology Faculty Of Agriculture Kyoto University

• Iwai Kazuo

  Laboratory Of Nutrition Chemistry Faculty Of Home Economics Kobe Women's University

• Hayakawa T

  Niigata Univ. Niigata Jpn

• Shibata Katsumi

  Food And Nutrition Laboratories Teikoku Wumen's University

• HAYAKAWA Takashi

  Laboratory of Nutritional Chemistry, Department of Food Science and Technology, Faculty of Agricultu

• Shibata Katsumi

  Food And Nutrition Laboratories Teikoku Women's University

• Hayakawa Takashi

  Laboratory Of Nutritional Chemistry Department Of Food Science And Technology Faculty Of Agriculture

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