磁気共鳴画像と反復有限要素解析に基づく生体軟組織の材料定数推定

概要

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This paper presents a method of material properties estimation for highly accurate finite element analysis of living soft tissue. It employs a compression test inside MRI in order to visualize the deformation of hypodermic structures, and an FE model of the compressed tissue in which the same boundary conditions as the compression test are assigned. The FE analysis is iterated with updated material constants until the difference between the two images, the observed MR image deformity and a synthesized deformed image, is minimized. The synthesized deformed image is obtained by warping the pre-compression MR image according to the displacement fields computed by the FE analysis. This method can, therefore, take subcutaneous structures and non-linear material characteristics of soft tissue into consideration. The estimated material constants guarantee high reproducibility of the FE analysis that can be evaluated in detail by comparing the two deformed images. This method is believed to be capable of conducting highly accurate FE analysis and its quantitative evaluation. The presented method was applied to a 3-layer silicon rubber sample. The results revealed that the performance of our method was excellent. The error in estimation was less than 7% for all layers, and the error in reproducibility of the FE analysis with the estimated material constants was confirmed to be 8%.
社団法人日本生体医工学会の論文
2005-12-10