紫斑病性腎炎の臨床病理学的検討
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概要
- 論文の詳細を見る
小児領域に多く,しかも我が国に発症率の高い紫斑病性腎炎について,臨床病理学的に検討した。対象は腎生検を施行し得た,2.2才から15.1才迄の男児28例,女児11例の39症例である。全例,Schoenlein-Henoch typeの紫斑病に腎炎を合併した症例である。39症例に対し追跡腎生検を含め52回の腎生検が施行された。全症例の臨床病理学的分類はTable 1,Table 10のごとくであるが,半月体形成を伴う糸球体の荒廃像が全糸球体の6割以上を占め,しかも臨床病態像がネフローゼ型を呈したものは予後不良であった。39症例中,腎移植に迄移行したものは2例,透析中死亡したもの1例,腎不全に移行しつつあるものは3例である。それ以外は4年以内にほとんどの症例が治癒もしくは臨床的に軽快している。昨今,本疾患はimmune complex type腎炎であるとして,注目され臨床病理学的に再検討の時期にあるが,少なくとも腎生検が施行され進行性腎炎の疑いがある場合は積極的治療(ステロイド剤を含めた免疫抑制剤の多剤少量併用治療)の対象になると考えられた。
- 北里大学の論文
- 1978-02-28
著者
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酒井 糾
泌尿器科学
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KASAI Noriaki
Department of Orthopedic Surgery, School of Medicine Kitasato University
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YOSHIDA Shigehiko
Department of Pediatric Surgery, Graduate School of Medicine, Tohoku University
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Tanaka Toshio
Department Of Respiratory Medicine Allergy And Rheumatic Disease Osaka University Graduate School Of
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酒井 糾
Department of Urology, Kitasato University School of Medicine.
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Adjei Sowah
Department of Child Health, University of Ghana Medical School, Africa.
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Igarashi Muneo
Department of Pediatrics, Kitasato University School of Medicine.
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Chen Tou-Hwei
Department of Pediatrics, National Taiwan University, School of Medicine.
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Yoshida Shigehiko
Department Of Pediatrics Kitasato University School Of Medicine.
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Yoshida Shigehiko
Department Of Cardiovascular Surgery Shin-katsushika Hospital
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Adjei Sowah
Department Of Child Health University Of Ghana Medical School Africa.
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Kasai Noriaki
Department Of Orthopedic Surgery School Of Medicine Kitasato University
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Chen Tou-hwei
Department Of Pediatrics National Taiwan University School Of Medicine Repubulic Of Chaina.
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Igarashi Muneo
Department Of Pediatrics Kitasato University School Of Medicine.
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Tanaka Toshio
Department Of Cardiology Matsusaka Central General Hospital
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Tanaka Toshio
Department Of Biomedical Laboratory Sciences Graduate School Of Health Sciences Tokyo Medical And De
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Tanaka Toshio
Department Of Pathology Kitasato University School Of Medicine.
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Tanaka Toshio
Department Of Applied Physics Faculty Of Engineering Tokyo University
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Kasai Noriaki
Department of Pediatrics, Kitasato University, School of Medicine.
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Tanaka Toshio
Department of Applied Chemistry, Faculty of Engineering, Osaka Univeristy
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