眼瞼閉鎖ラットの形態学 1.眼球および視神経

概要

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The purpose of the present study was to observe the morphological feature of eyeball, optic nerve, chiasm and tract in rats with naturally occurring ankyloblepharon. Twelve of 19 rats age 12-18 weeks lost inilateral eyebal. And two of them lost both eyeballs. In most of them, the optic nerve of normal side was also poorly developed. In only one case, the nerve did not organize the optic chasm and take an abnormal pathway. The orbit of rats without an eyeball was filled with a lump of fat. Prevalence of ankyloblepharon was dependent upon their age. In rats under 6weeks, the prevalence of ankyloblepharon was significantly lower than the older wats aged above 12 weeks. These findings suggest that rats with naturally occurred ankyloblepharon have narious pathologic observations. Thus, in future studies, it is necessary to examine the pathogenesis of them.
九州保健福祉大学の論文
2005-03-25