Bacillus cereusの産生する血管透過性亢進活性物質の精製と性状〔英文〕
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概要
- 論文の詳細を見る
Purification of an extracellular protein exhibiting the vascular permeability activity produced by Bacillus cereus was performed by ammonium sulfate precipitation followed by chromatography on DE-32 cellulose, Sephadex G-100, and Sephadex G-75. The purified protein was found to be electrophoretically and antigenically almost homogeneous although it contained a trace of contaminant. The molecular weight of the protein was calculated to be 45,000 by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. The purified protein showed vascular permeability activity and mouse lethal toxicity, and caused fluid accumulation in ligated mouse intestinal loops, whereas it did not show any hemolytic and lecithinase activities. From these findings, the purified protein is suggested to be an enterotoxin (or a diarrheagenic toxin) responsible for diarrhea caused by B. cereus in a diarrheal-type food poisoning.
- 社団法人日本獣医学会の論文
- 1991-04-15
著者
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Matsusaka N
Iwate Univ. Morioka Jpn
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Shinagawa Kunihiro
Department of Veterinary Microbiology, Faculty of Agriculture, Iwate University
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KONUMA Hirotaka
School of Marine Science and Technology, Tokai University
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MATSUSAKA Naonori
Departments of Veterinary Pharmacology and Veterinary Public Health, Iwate University,
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Matsusaka N
Iwate Univ. Morioka‐shi Jpn
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UENO Shunji
Department of Veterinary Public Health, School of Veterinary Medicine and Animal Sciences, Kitasato
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KONUMA Hirotaka
National Institute of Hygienic Sciences
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SUGII Shunji
Department of Serology and Immunology, School of Medical Technology, Kitasato University
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Ueno S
Kitasato Univ. Aomori Jpn
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Matsusaka Naonori
Department Of Veterinary Medicine Faculty Of Agriculture Iwate University
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Sugii Shunji
Laboratory Of Veterinary Microbiology Division Of Veterinary Science Graduate School Of Agriculture
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Konuma H
School Of Marine Science And Technology Tokai University
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Shinagawa Kunihiro
Department Of Veterinary Medicine Iwate University
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Shinagawa Kunihiro
Department Of Veterinary Medicine Faculty Of Agriculture Iwate University
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Matsusaka Naonori
Faculty Of Agriculture Iwate University
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品川 邦汎
Department of Veterinary Medicine, Faculty of Agriculture, Iwate University
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