Pyrimidine Derivatives and Related Compounds. XVI. Synthesis of 1,3-Disubstituted 5-Cyanouracil Derivatives and Related Compounds
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Ring closure reactions for synthesizing 1-substituted 5-cyanouracils, 3-substituted 5-cyanouracils, 1-substituted 5-carboxyuracils and 1-substituted 5-acetyluracils were investigated where substitutents were methyl, butyl, phenyl, and cyclohexyl. These compounds were then methylated in 1-or 3-position to give 1,3-disubstituted uracil derivatives which were useful as intermediates for drugs.
- 公益社団法人日本薬学会の論文
- 1972-07-25
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