抗うつ剤としてのDidenzo[b, e][1,4]diazepine誘導体の合成

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概要

• 論文の詳細を見る

• On the basis of earlier finding that an alkylsulfonyl group when introduced into simple benzene derivatives exerted a CNS activity, ethylsulfonyl derivatives of dibenzo [b, e]-[1,4] diazepines (VII, VIII, and X) were synthesized. A dimethylsulfamyl derivative (XX) was also prepared for comparison. VII (R=CH_3,n=2) was selected as a potent anti-depressant with low toxicity.

• 公益社団法人日本薬学会の論文
• 1969-02-25

著者

• 釘田 博至

  田辺製薬有機研究所

• 釘田 博至

  田辺製薬株式会社有機化学研究所

• 武田 幹男

  Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.

• 釘田 博至

  Organic Chemistry Research Laboratory:tanabe Seiyaku Co. Ltd.

• 武田 幹男

  田辺製薬株式会社有機化学研究所

• 松原 充

  田辺製薬株式会社有機化学研究所

関連論文

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