ミカン科植物アルカロイド研究(第19報) : アコウザンショウXanthoxylum inerme KOIDZ.(Fagara boninensis KOIDZ.)の成分その1 : 樹皮および木部の成分検索(有機化学)

概要

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Four compounds were isolated from the wood of Xanthoxylum inerme KOIDZ. (Fagara boninensis KOIDZ.), (Japanese name "Akow-zansho"). One is an alkaloid, 4-methoxy-1-methyl-2-quinolone (III), mp 99-103°, which was isolated for the first time from a natural source. Two others were known coumarins, 6,7,8-trimethoxycoumarin (I), mp 107-108°, and aesculetin dimethyl ether (II), mp 147-147.5°. The fourth was a phenolic lignan, dl-syringaresinol (VIII), mp 179-185.5°. On the other hand, seven components were isolated from the bark of the same plant. Four of them were benzo[c]phenanthridine alkaloids, nitidine (XI)(chloride, mp 275-276° : dihydro base (XII), mp 223.5-224°), avicine (XIV)(dihydro base (XIII), mp 223-224°). chelerythrine ψ-cyanide (X), mp 240-245°(decomp.), and oxynitidine (XV), mp 283-285°, assumed to be an artefact alkaloid. One was a water-soluble quaternary tetrahydrobenzylisoquinoline alkaloid, L-(+)-armepavine metho salt (XVIII) (iodide, mp 204-206°), which was isolated from natural source for the first time. The others were an unknown base, X. bon. unknown base I, mp 252-254.5°(decomp.), and aesculetin dimethyl ether (II).
公益社団法人日本薬学会の論文
1972-02-25