生薬の薬物学的研究(第8報) : 利尿生薬についての一考察

概要

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Examinations were made on about thirty kinds of diuretic crude drugs used as folk medicine, for their yield of extract decocted, quantitative determination of potassium, sodium and calcium contents by flame photometer, and their diuretic action on rats primed with saline. Some considerations were then made on the relationship between potassium content and diuretic action. The results of chemical examination are shown in Table I and Fig. 1. In the case of diuretic experiment, potassium acetate, potassium chloride, caffeine and aminophylline showed diuretic action remarkably, but all the diuretic crude drugs showed no action. Effective dose of potassium was higher than the maximum content dose contained in them. This result indicates that there might not be the close relationship between empirical diuretic action of the drugs and their potassium content in them.
日本生薬学会の論文
1964-01-20