アミンN-オキシドの関与する反応(第13報)Benzo[f, h and g]quinolineおよびAcridineと芳香族アミンN-オキシドとの反応

概要

論文の詳細を見る
Dehydrogenative condensation of two molecules of pyridine 1-oxide or N-oxides of benzo [f] quinoline (I), benzo [h] quinoline (IV), benzo [g] quinoline (VIII), and acridine (XIII) by hydrogenation using a platinized palladium-carbon catalyst affords respective dimers bonded at 2-position of the ring nitrogen, except in XIII which cannot undergo dehydrogenation at 2-position of the ring nitrogen. I and IV also afforded the corresponding pyridylbenzoquinoline, although in a small quantity. Dimerization of these compounds is extremely poor compared to pyridine and quinoline. IV formed its dimer only when 10-hydroxybenzo [h] quinoline was reacted as its N-oxide. VIII was synthesized by dehydrogenative aromatization of 6,7,8,9-tetrahydrobenzo [g] quinoline with DDQ and VIII was not formed when palladium-carbon was used, resulting in the formation of a dimer.
社団法人日本薬学会の論文
1979-12-25