シクロヘキシルおよびメンチル6'-O-トリチルグルコシドとそれらのアセチル誘導体の^1H-および^<13>C-核磁気共鳴スペクトル

概要

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The ^<13>C-nuclear magnetic resonance (^<13>C-NMR) spectra of cyclohexyl, d-, and l-menthyl 6'-O-tritylglucopyranosides and their acetyl derivatives, and the ^1H-NMR spectra of d-and l-menthyl 6'-O-tritylglucopyranoside acetates were recorded, and their signals were assigned. The effects of 6'-O-tritylation upon the conformation around the glycosidic linkage and upon the aglycon moiety were examined. It was found that the trityl group on the sugar moiety affected chemical shifts of the anomeric-proton and -carbon, and of the proton on the carbinyl-carbon and the carbinyl-carbon. Furthermore, ^1H-and ^<13>C-NMR chemical shifts of substituent groups on the aglycon moiety on 6'-O-tritylation suggested a relative conformation between sugar moiety and aglycon.
公益社団法人日本薬学会の論文
1983-09-25