Syntheses and ^1H- and ^<13>C-Nuclear Magnetic Resonance Spectra of All Positional Isomers of Tetra-O-acetyl-D-glucopyranoses, and Their Monobenzyl and Monotrityl Derivatives

概要

論文の詳細を見る
All the isomers of the tetra-O-acetyl-D-glucopyranoses, and their monobenzyl and monotrityl derivatives were synthesized and systematic ^1H- and ^<13>C-nuclear maghetic resonance (^1H-and ^<13>C-NMR) studies were carried ont. Complete assignments of the ^1H- and ^<13>C-NMR signals were achieved by ^1H[^1H]- and ^<13>C[^1H]-decoupling techniques and by the use of a shift reagent and changes of solvents. Moreover, when necessary, ^1H[^1H]- and ^<13>C[^1H]-shift-correlated 2D NMR spectroscopy at higher frequency (Bruker AM 400) was applied. The shifts on deacetylation, benzylation, and tritylation were estimated on the basis of the ^1H- and ^<13>C-chemical shifts of these compounds, and the effects of deacetylation and benzyl- or trityl-substitution are discussed.
公益社団法人日本薬学会の論文
1986-06-25