Reaction of Ethyl Acylindole-2-carboxylates with Thallium Trinitrate (Synthetic Studies on Indoles and Related Compounds. XXXIII)
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概要
- 論文の詳細を見る
Ethyl acylindole-2-carboxylates were treated with thallium trinitrate (TTN) in methanol, methyl orthoformate, methyl orthoformate/sulfuric acid, and acetic acid. The reactions in the former three methanolic solvents gave methyl indoleacetate derivatives via the Favorskii-type rearrangement reaction at the acyl group, whereas the reaction in acetic acid gave oxindole derivative with rearrangement of the C_2-ethoxycarbonyl group. The TTN reaction was applied to a model compound leading to the synthesis of lysergic acid.
- 公益社団法人日本薬学会の論文
- 1994-03-15
著者
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谷 正宣
School of Pharmaceutical Sciences, Toho University
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松本 茂信
School of Pharmaceutical Sciences, Toho University
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横山 祐作
School of Pharmaceutical Sciences, Toho University
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村上 泰興
School of Pharmaceutical Sciences, Toho University
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谷 正宣
School Of Pharmaceutical Sciences Toho University
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村上 泰興
東邦大・薬
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村上 泰興
School Of Pharmaceutical Science Toho University
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間 良幸
School of Pharmaceutical Sciences, Toho University
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有川 志保
School of Pharmaceutical Sciences, Toho University
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中根 敦子
School of Pharmaceutical Sciences, Toho University
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横山 祐作
東邦大学薬学部
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間 良幸
School Of Pharmaceutical Sciences Toho University
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松本 茂信
School Of Pharmaceutical Sciences Toho University
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有川 志保
School Of Pharmaceutical Sciences Toho University
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中根 敦子
School Of Pharmaceutical Sciences Toho University
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